(N-Barbituryl)phenyl- and cyclohexylalkanoic acids and some of their derivatives as potential anti-inflammatory agents.

A series of p-(N-barbituryl)phenyl- and cyclohexylalkanoic acids and their esters were synthesized. The preliminary pharmacological screening using the carrageenin, xylene and cotton tests revealed strong anti-inflammatory activity of several compounds in some of the tests performed, compound (Ij) being active in all the tests.