Effect of Maternal Nutritional Status and Mode of Delivery on Zinc and Iron Stores at Birth |
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Authors: | Oraporn Dumrongwongsiri Pattanee Winichagoon Nalinee Chongviriyaphan Umaporn Suthutvoravut Veit Grote Berthold Koletzko |
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Institution: | 1.Center for International Health, Ludwig-Maximilians-Universitaet Munich, 80336 Munich, Germany;2.Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand; (N.C.); (U.S.);3.Institute of Nutrition, Mahidol University, Nakhon Pathom 73170, Thailand;4.Department of Pediatrics, Dr. von Hauner Children’s Hospital, University Hospital, Ludwig-Maximilians-Universitaet Munich, 80337 Munich, Germany; (V.G.); (B.K.) |
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Abstract: | Zinc and iron deficiencies among infants aged under 6 months may be related with nutrient store at birth. This study aimed to investigate the association between zinc and iron stores at birth with maternal nutritional status and intakes during pregnancy. 117 pregnant women were enrolled at the end of second trimester and followed until delivery. Clinical data during pregnancy, including pre-pregnancy body mass index (BMI) and at parturition were collected from medical record. Zinc and iron intakes were estimated from a food frequency questionnaire. Serum zinc and ferritin were determined in maternal blood at enrollment and cord blood. Mean cord blood zinc and ferritin were 10.8 ± 2.6 µmol/L and 176 ± 75.6 µg/L, respectively. Cord blood zinc was associated with pre-pregnancy BMI (adj. ß 0.150; p = 0.023) and serum zinc (adj. ß 0.115; p = 0.023). Cord blood ferritin was associated with pre-pregnancy BMI (adj. ß −5.231; p = 0.009). Cord blood zinc and ferritin were significantly higher among those having vaginal delivery compared to cesarean delivery (adj. ß 1.376; p = 0.007 and 32.959; p = 0.028, respectively). Maternal nutritional status and mode of delivery were significantly associated with zinc and iron stores at birth. Nutrition during preconception and pregnancy should be ensured to build adequate stores of nutrients for infants. |
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Keywords: | cord blood zinc cord blood ferritin iron deficiency zinc deficiency nutrition in pregnancy pre-pregnancy BMI |
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