Nearly identical strains of human herpesvirus 8 in couples discordant for Kaposi's sarcoma |
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Authors: | Kouri Vivian Marini Alessandra Nambiar Sandeep Rodriguez Maria E Capo Virginia Resik Sonia Mantecon Beatriz Martinez Ariel Köhler-Hansner Karin J Hengge Ulrich R |
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Institution: | Instituto de Medicina Tropical Pedro Kouri, Ciudad de La Habana, Cuba. |
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Abstract: | Transmission of human herpesvirus 8 (HHV-8) may occur through various routes including breastfeeding and sexual intercourse. We attempted to detect HHV-8 infection in nine HIV-positive couples discordant for Kaposi's sarcoma who maintained a monogamous sexual relationship for at least one year. By quantitative real-time polymerase chain reaction and HHV-8 genotyping we provide strong evidence for the sexual transmission of HHV-8 in this unique cohort. |
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