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Nearly identical strains of human herpesvirus 8 in couples discordant for Kaposi's sarcoma
Authors:Kouri Vivian  Marini Alessandra  Nambiar Sandeep  Rodriguez Maria E  Capo Virginia  Resik Sonia  Mantecon Beatriz  Martinez Ariel  Köhler-Hansner Karin J  Hengge Ulrich R
Institution:Instituto de Medicina Tropical Pedro Kouri, Ciudad de La Habana, Cuba.
Abstract:Transmission of human herpesvirus 8 (HHV-8) may occur through various routes including breastfeeding and sexual intercourse. We attempted to detect HHV-8 infection in nine HIV-positive couples discordant for Kaposi's sarcoma who maintained a monogamous sexual relationship for at least one year. By quantitative real-time polymerase chain reaction and HHV-8 genotyping we provide strong evidence for the sexual transmission of HHV-8 in this unique cohort.
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