心脏再同步化治疗慢性心力衰竭疗效观察

目的:探讨心脏再同步化治疗(CRT)慢性心力衰竭临床疗效。方法:6例慢性心力衰竭(CHF)患者行双心室再同步起搏治疗,术后随访10.2±6.3个月,观察患者的NYHA心功能分级、QRS时限、左心室射血分数(LVEF)、左心室舒张末内径(LVEDD)的变化。结果:6例CHF患者植入CRT后,均无严重并发症,心功能NYHA分级,从～级改善为～级,QRS时限从158.6±31.8ms缩短至129.5±30.2ms(P<0.05),LVEF从0.28±0.05提高至0.35±0.05(P<0.05),LVEDD由术前71.93±10.79mm降至术后65.55±12.35mm(P<0.05)。结论:CRT结合药物优化治疗,可明显改善慢性顽固性心力衰竭患者的血流动力学、心功能和心衰的临床症状,提高生活质量。

Clinical observation of cardiac resynchronization therapy for patients with chronic heart failure

Objective：To observe the clinical effect of cardiac resynchronization therapy（CRT） in patients with chronic heart failure（CHF）. Methods： 6 patients with chronic refractory heart failure accompanied by intraventricular conduction delay were selected to reseive resynchronous biventricular pacing.Changes of NYHA functional class,QRS duration,left ventricular ejection fraction （LVEF）,left ventricular end diastolic diameter （LVEDD）were observed after 10.2±6.3 months follow-up. Results： 6 patients was good after the treatment.NYHA fuctional class was obviously improved to II~III from III~IV.QRS duration was obviously decreased to 129.5±30.2ms from 158.6±31.8ms.LVEF was obviously increased to 0.35±0.05 from 0.28±0.05.LVEDD was decreased to 65.55±12.35mm from 71.93±10.79mm. Conclusion：CRT with medicine that can improve hemodynamics,cardiac function,clinical symptoms and quality of life in patients with chornic refractory heart failure.