| 托吡酯治疗各类癫痫的疗效观察 |
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| 引用本文： | 周绍洪. 托吡酯治疗各类癫痫的疗效观察[J]. 中国药房, 2011, 0(36): 3438-3439 |
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| 作者姓名： | 周绍洪 |
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| 作者单位： | 重庆骑士医院神经内科; |
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| 摘 要： | 目的:观察托吡酯单药治疗各类癫痫的临床疗效及安全性。方法:将我院2007年1月-2010年1月250例癫痫患者使用托吡酯单药治疗后的疗效进行统计、分析,并评价其安全性。结果:治疗后发作完全控制者68例(27.2%),显效64例(25.6%),有效56例(22.4%),总有效率为75.2%。治疗期间分别发生记忆力下降(13.6%)、体重减轻(8.8%)、恶心(7.2%)、言语障碍(5.6%)、嗜睡(4.8%)、头昏(4.4%)、低热(3.2%)、肾结石(2.8%)等不良反应。结论:托吡酯单药治疗癫痫疗效显著,完全控制率高,不良反应较轻。
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| 关 键 词： | 癫痫 托吡酯 控制发作 |
Efficacy Observation of Topiramate in the Treatment of Various Types of Epilepsy |
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| ZHOU Shao-hong. Efficacy Observation of Topiramate in the Treatment of Various Types of Epilepsy[J]. China Pharmacy, 2011, 0(36): 3438-3439 |
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| Authors: | ZHOU Shao-hong |
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| Affiliation: | ZHOU Shao-hong(Dep.of Neurology,Chongqing Knight Hospital,Chongqing 400021) |
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| Abstract: | OBJECTIVE:To observe the topiramate monotherapy clinical efficacy and safety of various types of epilepsy.METHODS:A retrospective analysis in Jan.2007-Jan.2010 of 250 cases of epilepsy patients with topiramate monotherapy treatment was analyzed.The clinical efficacy and safety was statistics analysis.RESULTS:Complete control of seizures in 68 cases,accounting for 27.2%;64 cases were markedly improved(25.6%);56 cases were effective(22.4%),total efficiency was 75.2%.Memory loss(13.6%),weight loss(8.8%),nausea... |
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| Keywords: | Epilepsy Topiramate Control seizures |
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