| 阿托伐他汀治疗冠心病合并高脂血症的临床观察 |
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| 引用本文： | 王栋.阿托伐他汀治疗冠心病合并高脂血症的临床观察[J].中国药房,2011(36):3426-3428. |
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| 作者姓名： | 王栋 |
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| 作者单位： | 海南文昌市人民医院心血管内科; |
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| 摘 要： | 目的:观察阿托伐他汀治疗冠心病合并高脂血症的临床疗效。方法:选取我院2008年6月-2010年9月213例确诊为冠心病合并高脂血症的患者为研究对象,随机分为治疗组(113例)和对照组(100例),2组均按冠心病伴高脂血症常规内科治疗,治疗组加用阿托伐他汀20mg,qd,口服。2组均8周为一疗程。治疗前后进行血、尿常规,血糖及肝、肾功能,心电图等指标检测,并对比其疗效。结果:治疗8周后,治疗组总胆固醇、甘油三酯、低密度脂蛋白、C反应蛋白、白细胞介素-6、肿瘤坏死因子-α、vonWill-ebrand因子、内皮素均较治疗前显著下降,高密度脂蛋白及一氧化氮均显著升高,治疗前后比较,差异有统计学意义(P<0.05),而对照组治疗前后上述指标比较无显著性差异(P>0.05);治疗组治疗后显效率及总有效率分别为77.0%和95.6%,与对照组(61.0%和76.0%)比较,差异有统计学意义(P<0.05)。结论:阿托伐他汀治疗冠心病合并高脂血症疗效确切,不良反应少。
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| 关 键 词： | 阿托伐他汀 冠心病 高脂血症 |
Clinical Observation of Atorvastatin in the Treatment of Coronary Heart Disease Complicating with Hyperlipidemia |
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| WANG Dong.Clinical Observation of Atorvastatin in the Treatment of Coronary Heart Disease Complicating with Hyperlipidemia[J].China Pharmacy,2011(36):3426-3428. |
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| Authors: | WANG Dong |
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| Institution: | WANG Dong(Dept.of Cardiology,Wenchang Municipal People's Hospital of Hainan Province,Wenchang 571300,China) |
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| Abstract: | OBJECTIVE:To observe the clinical efficacy of atorvastatin in the treatment of coronary heart disease(CHD) complicating with hyperlipidemia.METHODS:213 cases of CHD complicating with hyperlipidemia from Jun.2008 to Sept.2010 were randomly divided into treatment group(113 cases) and control group(100 cases).Both groups were given conventional therapy for CHD complicating with hyperlipidemia.Treatment group was additionally treated with atorvastatin 20 mg,qd,p.o.for 8 weeks.A treatment course lasted for 8 wee... |
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| Keywords: | Atorvastatin Coronary heart disease Hyperlipidemia |
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