集束电极射频治疗肺癌效果的CT评估

目的　CT评价集束电极射频治疗肺癌的近期疗效。方法　对 6 8例肺癌患者通过集束电极射频治疗用CT比较手术前后肿瘤大小和密度的变化。结果　 6 8例肺癌 70个病灶射频治疗术前、术后 30min和术后 6 0d进行CT复查。单点治疗组 :病灶的体积在术后 30min增大明显 ,在术后 6 0d缩小 ,治疗前后病灶最大径分别为 (4.15± 0 .97)cm ,(5 .5 4± 1.37)cm和 (2 .79± 0 .6 8)cm ,有显著性差异 (P <0 .0 5 )。多点治疗组 :病灶的体积在 30min增加不显著 ,在 6 0d缩小不明显 ,病灶最大径分别为 (8.0 6±1.91)cm ,(9.13± 1.78)cm和 (7.6 3± 2 .16 )cm ,无显著性差异 (P >0 .0 5 )。病灶CT值在术后 30min和术后 6 0d均减低 ,单点治疗组 :治疗前、治疗后 30min及 6 0d的密度值分别为 :(49.6± 6 .2 )Hu ,(40 .5±14.4)Hu和 (35 .2± 3.2 )Hu ;多点治疗组分别为 :(46 .7± 5 .3)Hu ,(37.4± 11.8)Hu ,(35 .1± 2 .3)Hu ,以上均有显著性差异 (P <0 .0 5 )。结论　CT可判定肺癌集束电极射频治疗前后病灶大小变化和密度变化 ,给肺癌射频治疗的预后提供重要参数 ,为重复治疗提供依据

CT investigation of lung neoplasm changes after cluster electrode radio frequency ablation

Objective　To evaluate short-term therapeutic effect of lung neoplasm after cluster electrode radio frequency ablation. Methods　CT scans were performed in 68 cases with lung neoplasm to investigate the alterations of tumor size and density pre- and post-procedure. Results　Seventy lesions in 68 cases with lung neoplasm were observed by CT pre-procedure and 30min after the procedure, while the follow-up was taken place after 60d. In mono-target group, size of the lesion was increased 30min after the procedure and decreased after 60d, the sizes were (4.15±0.97)cm, (5.54±1.37)cm and (2.79±0.68)cm, respectively, There were significant differences between them(P<0.05). In multi-target group, the size showed no significant increase 30min after the procedure and no decrease after 60d, they were (8.06±1.91)cm, (9.13±1.78)cm and (7.63±2.16)cm, respectively(P>0.05). The density of the lesions were lessened both 30min and 60d after the procedure. In mono-target group, the average density of lesions in different times were (49.6±6.2)Hu, (40.5±14.4)Hu and (35.2±3.2)Hu, respectively, while they were (46.7±5.3)Hu, (37.4±11.8)Hu, (35.1±2.3)Hu, respectively, in multi-target. There were significant differences(P<0.05). Conclusions　CT scan is an useful method to observe size and density of lung neoplsm after the procedure of cluster electrode radio frequency ablation providing information of objective parameters and prediction of prognosis.