| 拉莫三嗪联合氟西汀与氟西汀单独治疗抑郁症的临床观察 |
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| 引用本文： | 张陆云,张丽莎,刘玉元,崔中兰. 拉莫三嗪联合氟西汀与氟西汀单独治疗抑郁症的临床观察[J]. 中国民康医学, 2005, 17(6): 271-272 |
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| 作者姓名： | 张陆云 张丽莎 刘玉元 崔中兰 |
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| 作者单位： | 山东省滨州市人民医院,山东 滨州 256613 |
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| 摘 要： | 目的探讨拉莫三嗪联合氟西汀治疗抑郁症的效果。方法:随机将68例抑郁症患者分成两组,分别给予拉莫三嗪联合氟西汀单独应用氟西汀治疗8周;以汉密尔顿抑郁量表(HAMD)评定疗效,以副反应量表(TESS)评定副反应。结果:两组间HAMD于第2、4、6、8周末减分率比较,差异均有显著性(P<0. 01 /P<0. 05)。两组间TESS评分各周差异均不明显。结论: 拉莫三嗪联合氟西汀治疗抑郁症疗效优于单纯使用氟西汀,且耐受性好。
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| 关 键 词： | 抑郁症 拉莫三嗪 氟西汀 |
| 文章编号： | 0369(2005)06-0271-02 |
| 修稿时间： | 2004-12-08 |
A clinical study of lamotrigine combined with fluoxetine and fluoxetine alone in the treatment of depression |
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| ZHANG Lu-yun,ZHANG Li-Sha,LIU Yu-yuan,CUI Zhong-lan. A clinical study of lamotrigine combined with fluoxetine and fluoxetine alone in the treatment of depression[J]. medical journal of chinese peoples health, 2005, 17(6): 271-272 |
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| Authors: | ZHANG Lu-yun ZHANG Li-Sha LIU Yu-yuan CUI Zhong-lan |
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| Abstract: | Objective:To explore the effect of lamotrigine combined with fluoxetine in the treatment of depression. Methods: A total of 68 patients with depression were randomly assigned into two groups, one group treated with lamotrigine combined with fluoxetine. The other with fluoxetine alone for 8 weeks. The efficacy and side effects were evaluated with HAMD and TESS in 1,2,4,6,8 weeks after treatment. Results: There were significant difference on decreased rates of HAMD between two groups in 2,4,6,8 weeks after treatment (P<0.01/P<0.05). There was no difference on scores of TESS between two groups. Conclusions: Lamotrigine combined with fluoxetine had better efficacy with good tolerance. |
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| Keywords: | Depression Lamotrigine Fluoxetine |
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