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核素32P胶体灌注治疗慢性上颌窦炎22例报告
引用本文:王胜利,计学理,肖来华,赵晓宇,耿建,刘建功,曹立新.核素32P胶体灌注治疗慢性上颌窦炎22例报告[J].临床耳鼻咽喉头颈外科杂志,2001,15(11):494-495.
作者姓名:王胜利  计学理  肖来华  赵晓宇  耿建  刘建功  曹立新
作者单位:1. 北京铁路局大同铁路中心医院耳鼻咽喉科,
2. 北京铁路局大同铁路中心医院核医学科
摘    要:目的探讨核素32P胶体对慢性上颌窦炎的治疗作用.方法对22例(31侧)慢性上颌窦炎患者先行窦腔冲洗,然后以32P胶体窦内灌注治疗.并与行常规保守治疗的20例(31侧)患者进行对照比较.结果核素组治愈27侧,治愈率87%,复发4侧;常规组治愈1 9侧,治愈率61%,复发12侧.经统计学处理,P<0.01.核素组疗效明显优于常规组.结论核素32P胶体对病变组织的电离辐射作用可使免疫活性和组织代谢过程增强,使局部微小血管和微淋巴管闭塞,促进炎性组织渗液吸收,渗出减少,水肿消失,使增生组织逐渐萎缩,对慢性炎症有促进愈合的作用.

关 键 词:慢性上颌窦炎  磷放射性同位素  放射疗法
文章编号:1001-1781(2001)11-0494-02
修稿时间:2001年4月23日

Treatment of nuclein 32p colloid perfusion with chronic suppurative maxillary sinusitis
WANG Shengli,JI Xueli,XIAO Laihua,ZHAO Xiaoyu,GENG Jian,LIU Jiangong,CAO Lixin.Treatment of nuclein 32p colloid perfusion with chronic suppurative maxillary sinusitis[J].Journal of Clinical Otorhinolaryngology,2001,15(11):494-495.
Authors:WANG Shengli  JI Xueli  XIAO Laihua  ZHAO Xiaoyu  GENG Jian  LIU Jiangong  CAO Lixin
Institution:Department of Otolaryngology, Datong Railway Hospital, Datong 037005.
Abstract:OBJECTIVE: To determine the effect of nuclein 32P colloid in treatment of chronic maxillary sinusitis (CMS). METHOD: 22 patients (31 sides) with CMS after washing of sinucavity were perfused with nuclein 32P in sinucavity. 20 patients (31 sides) with routine conservative treatment were served as a control group. Two groups were followed up for one year. RESULT: In nuclein group, 27 sides were cured, 4 sides were recurred and the rate of cure was 87%. In routine group, 19 sides were cured, 12 sides were recurred and the rate of cure is 61%. There is significant difference between the two groups (P < 0.01). The treatment active of nuclein group is better than that of routine group. CONCLUSION: Nuclein 32P colloid with the function of ionizing radiation can increase the pathogenic tissue immunocompetence and metabolic course, obstruct the microvascular and promote the absorption of inflammatory exudation and edema subsidence. It can also make the proliferous tissue atrophy thence accelerate the rate of cure of CMS.
Keywords:Chronic  maxillary  sinusitis  Phosphorus radioisotopes  Radiotherapy
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