| 红细胞膜Na~+-K~+-ATP酶活性与动脉硬化性脑梗塞的关系 |
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| 引用本文： | 李智文,许国英,卓孝福,吴秀丽.红细胞膜Na~+-K~+-ATP酶活性与动脉硬化性脑梗塞的关系[J].中国动脉硬化杂志,1998,6(3):243-245. |
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| 作者姓名： | 李智文 许国英 卓孝福 吴秀丽 |
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| 作者单位： | 福建医科大学附属第一医院神经内科!福建，350005(李智文，许国英，吴秀丽)，福建医科大学检验系(卓孝福) |
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| 摘 要： | 为探讨红细胞膜Ｎａ＾＋－Ｋ＾＋－ＡＴＰ酶活性与动脉硬化性脑梗塞的关系，本文检测了３７例动脉硬化性脑梗塞患者、２０例脑动脉硬化症患者和２５例健康对照者的红细胞膜Ｎａ＾＋－Ｋ＾＋－ＡＴＰ酶活性，并将酶活性与脑ＣＴ梗塞灶大小进行直线回归分析。结果发现，动脉硬化性脑梗塞和脑动脉硬化症患者的Ｎａ＾＋－Ｋ＾＋－ＡＴＰ酶活性明显降低，酶活性降低程度与脑ＣＴ梗塞灶大小呈显著负相关性（ｒ＝－０．５８，Ｐ〈０．０１）
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| 关 键 词： | 脑梗塞 脑动脉硬化症 红细胞 ATP酶 |
| 收稿时间： | 1998/5/10 0:00:00 |
| 修稿时间： | 1998/7/31 0:00:00 |
Relationship between the Activity ofNa ~+-K~+ -ATPase on Erythrocyte Membrane and Arteriosclerotic Cerebral Infarction |
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| LI,Zhi-Wen; XU Gu-Ying;ZHUO Xiao-Fu and WUXiu-Li.Relationship between the Activity ofNa ~+-K~+ -ATPase on Erythrocyte Membrane and Arteriosclerotic Cerebral Infarction[J].Chinese Journal of Arteriosclerosis,1998,6(3):243-245. |
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| Authors: | LI Zhi-Wen; XU Gu-Ying;ZHUO Xiao-Fu and WUXiu-Li |
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| Institution: | LI Zhi-Wen, XU Gu0-Ying,ZHUO Xiao-Fu and WUXiu-Li |
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| Abstract: | To study the correlation between the activity of Na+-K+ -ATPase on erythrocyte membrane and arteriosclerotic cerebral infarction. Activity of Na+-K+ -ATPase on erythrocyte membrane was determined in 37 cases of arteriosclerotic cerebral infarction (ACI)and 25 normal control subjects. Activity of Na+ -K+-ATPase on erythrocyte membrane in ACI was obviously lower than that of control (P<0. 001), and the activity of Na+ -K+ -ATPase on erythrocyte membrane was negative correlated with infarct size on brain CT scans in ACI(r= -0. 58, P<0. 01).It suggested that the reduced activity of Na+ -K +-ATPase on erythrocyte membrane may have some ef-fect in the development of ACI. |
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| Keywords: | Cerebral infarction Cerebral arte-riosclerosis Erythrocyte Na +-K+- ATPase |
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