Immunological status in Huntington's disease. |
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| Authors: | U Fiszer K Piotrowska J Korlak A Cz?onkowska |
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| Affiliation: | Department of Cerebrovascular Disease, Institute of Psychiatry and Neurology, Warsaw, Poland. |
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| Abstract: | The immunological status of patients with Huntington's disease was studied and compared with that of an age-matched control group. No remarkable abnormalities in lymphocyte subpopulations were observed. The percentage of B cells, CD4+, CD8+, DR+ cells and stimulated cells bearing Tac receptors remained unchanged. The proliferative response to mitogens and the production of interleukin-1 (Il-1) were decreased, whereas the IgG level was increased. It is possible that changes in the levels of neurotransmitters affect the immunological function in basal ganglia disease. |
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