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Morbidity of peripherally inserted central catheters in pediatric complicated appendicitis
Authors:Jason P Sulkowski  Lindsey Asti  Jennifer N Cooper  Brian D Kenney  Mehul V Raval  Shawn J Rangel  Katherine J Deans  Peter C Minneci
Institution:1. Department of Surgery, Nationwide Children''s Hospital, Columbus, Ohio;2. Center for Surgical Outcomes Research, The Research Institute, Nationwide Children''s Hospital, Columbus, Ohio;3. Department of Surgery, Children''s Hospital Boston, Boston, Massachusetts
Abstract:

Background

The purpose of this study was to compare postoperative outcomes of pediatric patients with complicated appendicitis managed with or without a peripherally inserted central catheter (PICC).

Methods

Patients aged ≤18 y in the Pediatric Health Information System database with complicated appendicitis that underwent appendectomy during their index admission in 2000–2012 were grouped by whether they had a PICC placed using relevant procedure and billing codes. Rates of subsequent encounters within 30 d of discharge along with associated diagnoses and procedures were determined. A propensity score–matched (PSM) analysis was performed to account for differences in baseline exposures and severity of illness.

Results

We included 33,482 patients with complicated appendicitis; of whom, 6620 (19.8%) received a PICC and 26,862 (80.2%) did not. The PICC group had a longer postoperative length of stay (median 7 versus 5 d, P < 0.001) and were more likely to undergo intra-abdominal abscess drainage during the index admission (14.4% versus 2.1%, P < 0.001), and have a reencounter (17.5% versus 11.4%, P < 0.001) within 30 d of discharge. However, in the PSM cohort (n = 4428 in each group), outcomes did not differ between treatment groups, although the PICC group did have increased odds for the development of other postoperative complications (odds ratio = 3.95, 95% confidence interval: 1.45, 10.71).

Conclusions

After accounting for differences in severity of illness by PSM, patients managed with PICCs had a similar risk for nearly all postoperative complications, including reencounters. Postoperative management of pediatric complicated appendicitis with a PICC is not clearly associated with improved outcomes.
Keywords:Appendicitis  Complicated appendicitis  PICC  Peripherally inserted central catheter  PHIS  Pediatric Health Information System
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