术前淋巴结显像在乳腺癌前哨淋巴结活检中的应用价值

目的]探讨术前淋巴显像在乳腺癌前哨淋巴结活检中的应用价值。方法]回顾性分析2010年7月至2013年8月在河南省肿瘤医院行前哨淋巴结活检术的乳腺癌患者1041例，其中483例患者术前行淋巴结显像，558例患者未行淋巴显像而术中直接行前哨淋巴结活检术。结果]在淋巴显像组中，84.3％（407／483）的患者显像成功，该组SLNB的成功率为98．9％（478／483）。而在未行淋巴显像组中SLNB的成功率为98．7％（551／558）。两组SLNB检出成功率差异无统计学意义（P=0．78）。即使术前淋巴显像失败，其SLNB的检出成功率仍达到98．7％。结论]术前淋巴显像并不能提高SLNB的成功率。因此，临床工作中行前哨淋巴结活检前，淋巴显像不是必备条件。

Application Value of Preoperative Lymphoscintigraphy and Sentinel Lymph Node Biopsy in Patients with Breast Cancer

Purpose] To explore application value of preoperative lymphoscintigraphy and sentinel lymph node biopsy in breast cancer patients. Methodsl A total of 1041 cases with breast cancer accepted sentinel lymph node biopsy （SLNB） from Henan Cancer Hospital from July 2010 to August 2013 were analyzed retrospectively. Four hundred and eighty-three cases of them received preoperative lymphoscintigraphy,but 558 cases of them accepted SLNB without preoperative lymphoseintigraphy. Resuhs] In preoperative lymphoseintigraphy group,sentinel lymph nodes （SLN） were well im- aged by lymphoscintigraphy in 84.3%（407/483） of them,the successful rate of SLNB was 98.9%（478/ 483）;while the rate of 98.7%（551/558） in the group without preoperative lymphoscintigraphy. There was no significant statistically difference between the two groups（P=0.78）. Even preoperative lymphoscintigraphy failure detection,the success rate of SLNB still reached 98.7%.Conclusion] Preoperative lymphoscintigraphy doesn＇t improve the successful rate of SLN identification,so it is not necessary to use preoperative lymphoscintigraphy before SLNB in early breast cancer.