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肺癌病人血清硒的测定和分析
引用本文:朱长文 毛筱芬. 肺癌病人血清硒的测定和分析[J]. 徐州医学院学报, 1990, 10(3): 177-180
作者姓名:朱长文 毛筱芬
作者单位:徐州医学院化学教研室(朱长文),徐州医学院附院内科(毛筱芬)
摘    要:

关 键 词:肺癌 血清测定 硒

DETECTION AND ANALYSIS OF SELENIUM IN SERA OF LUNG CANCER PATIENTS
Zhu Changwen and Mao Xiaofen. DETECTION AND ANALYSIS OF SELENIUM IN SERA OF LUNG CANCER PATIENTS[J]. Acta Academiae Medicinae Xuzhou, 1990, 10(3): 177-180
Authors:Zhu Changwen and Mao Xiaofen
Abstract:An electroanalytical chemistry method, the Cathodic StridPing Voltammetryof 2.5th Order Defferential, was applied for the detection of serum selenium ( Se ) . The Procedure was carried out in the medium of 4.5 M HC1 and the working electrode was a hanging mercury drop electrode of model JM-01. The minimal detectable Quantity of selenium by the method was 0.05 PPb, so the accuracy and precision of the method meets the requirement of trace quantitative analysis. By usiug this method, the serum selenium concentration in 31 patients with lung cancer and 11 healthy controls was determined.Results showed that serum selenium concentration in the Patient group was significantly lower then in the control ( p<0.001 ) . The effect of serum selenium on the Pathogenesis of cancer and the therapeutic Potential of supplementary selenium in Preventing and curing it are discussed.
Keywords:lung  cancer   selenium  analysis  
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