| 晚期胰腺癌的化疗 |
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| 引用本文： | 林榕波,陈强,范南峰.晚期胰腺癌的化疗[J].国际肿瘤学杂志,2008,35(4). |
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| 作者姓名： | 林榕波 陈强 范南峰 |
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| 作者单位： | 福建省肿瘤医院内科,福州,350014 |
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| 摘 要： | 单药吉西他滨是晚期胰腺癌的标准治疗,但疗效并不理想.吉西他滨已与多种细胞毒药物或生物靶向药物组成多个联合方案,但是在大多数Ⅲ期临床研究中这些联合方案对生存时间的延长并没有超过吉西他滨单药.有Ⅲ期临床研究结果显示埃罗替尼联合吉西他滨可延长晚期胰腺癌患者的生存时间.非吉西他滨的化疗方案也正在评估中,并已初步看到了希望.
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| 关 键 词： | 胰腺肿瘤 药物疗法 |
Chemotherapy for advanced pancreatic cancer |
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| LIN Rong-bo,CHEN Qiang,FAN Nan-feng.Chemotherapy for advanced pancreatic cancer[J].Journal of International Oncology,2008,35(4). |
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| Authors: | LIN Rong-bo CHEN Qiang FAN Nan-feng |
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| Abstract: | Single-agent gemcitabine, the standard chemotherapy for pancreatic cancer, has only mod-est effect. Gemcitabine has been combined with a variety of cytotoxic agents and targeted agents. Most phase Ⅲ studies, however, have failed to show improved survival compared with gemcitabine alone. One phase Ⅲ study has shown improved survival in advanced pancreatic cancer by adding erlotinib to gemcitabine. Studies evalua-ting non-gemcitabine-based regimens have showed considerable promise. |
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| Keywords: | Pancreatic neoplasms Drug therapy |
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