| 葛根素注射液对早期糖尿病肾病患者血液流变学和可溶性粘附分子-1的影响 |
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| 引用本文： | 白立炜,翁孝刚,索新华,张清贵.葛根素注射液对早期糖尿病肾病患者血液流变学和可溶性粘附分子-1的影响[J].医学信息,2008,21(7). |
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| 作者姓名： | 白立炜 翁孝刚 索新华 张清贵 |
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| 作者单位： | 新乡医学院第一附属医院内分泌科,河南卫辉453100 |
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| 摘 要： | 目的观察葛根素注射液对早期糖尿病肾病患者血液流变学和血清可溶性细胞粘附分子-1（SICAM-1）的影响。方法将76例早期糖尿病肾病患者随机分为治疗组（42例）和对照组（34例）。两组均采用饮食控制和糖尿病常规治疗，治疗组加用葛根素注射液治疗，疗程3周。结果治疗组血液流变学各项指标较治疗前显著下降（P〈0．05）；尿白蛋白排泄率、血可溶性粘附分子-I（sICAM-1）均明显下降（P〈0．01），且明显优于对照组（P〈0．05）。结论葛根索注射液能改善早期糖尿病肾病患者的血液流变性和微循环，减少尿白蛋白的排出，降低血清sICAM-1水平，减轻肾损害。
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| 关 键 词： | 糖尿病肾病 葛根素注射液 血液流变学 可溶性细胞粘附分子-1 |
The effects of puerarin injection on changes of hemorrheology and soluble adhesion molecule-1 in patients with early diabetic nephropathy(EDN) |
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| BAI Li-wei,WENG Xiao-gang,SUO Xin-hua,et al.The effects of puerarin injection on changes of hemorrheology and soluble adhesion molecule-1 in patients with early diabetic nephropathy(EDN)[J].Medical Information,2008,21(7). |
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| Authors: | BAI Li-wei WENG Xiao-gang SUO Xin-hua |
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| Institution: | BAI Li-wei,WENG Xiao-gang,SUO Xin-hua,et al(Department of Endocrinology,the First Affiliated Hospital of Xinxiang Medical University,Weihui 453100,Henan Province,China) |
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| Abstract: | Objective To observe the influence of treatment with puerarin injection on changes of hemorrheology and serum soluble intercellular adhesion molecule-1(sICAM-1)in patients with early diabetic nephropathy(EDN).Methods Seventy-six patients with early diabetic nephropathy were randomly divided into two groups.The control group(n=34)was treated with conventional therapy for diabetes and diet control method,while the treatment group(n=42)was treated with puerarin injection additionally.The therapeutic course was... |
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| Keywords: | diabetic nephropathy puerarin injection hemorrheology soluble intercellular adhesion molecule-1 |
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