| 氨苄青霉素对丁胺卡那霉素药动学的影响 |
| |
| 引用本文： | 阚全程 秦玉花. 氨苄青霉素对丁胺卡那霉素药动学的影响[J]. 中国医院药学杂志, 1995, 15(7): 296-298 |
| |
| 作者姓名： | 阚全程 秦玉花 |
| |
| 作者单位： | 河南医科大学附属第一医院，河南省人民医院 |
| |
| 摘 要： | 本文采用微量微生物法对ＡＭＫ单用及ＡＭＫ与ＡＭＰ合用后，兔体内ＡＭＫ血、尿药浓度进行测定；药时数据用ＭＣＰＫＰ软件经ＩＢＭ计算机处理，并对两组药动学参数进行了统计学处理。结果表明ＡＭＰ对ＡＭＫ的药动学有显著的影响。
|
| 关 键 词： | 丁胺卡那霉素 氨苄青霉素 微生物法 药物动力学 |
Influence of ampicillinum on pharmacokinetics of amikacin |
| |
| Kan Quan-cheng,Qin Yu-hua. Influence of ampicillinum on pharmacokinetics of amikacin[J]. Chinese Journal of Hospital Pharmacy, 1995, 15(7): 296-298 |
| |
| Authors: | Kan Quan-cheng Qin Yu-hua |
| |
| Abstract: | Amikacin(AMK)in the serum was determined by the improved microbiology method for rabbits having injected in venousAMK or AMK combined with ampicillinum (AMP).The serum concentration were disposed with MCPKP propam and IBM mi-crocomputer.The pharmacokinetics parameters in two groupe were computed and sorted by statistic method. The resultsshowed that AMP had apparent influence on pharmacokinetics of AMK in rabbits. |
| |
| Keywords: | amikacin ampicillinum improved microhbiology method pharmacokinetics |
| 本文献已被 CNKI 维普 等数据库收录！ |
