地塞米松加芦荟外敷预防盖诺化疗致静脉损伤的效果观察

目的对86例盖诺(长春瑞宾)化疗患者,采取不同的静脉预防性保护。方法采用随机分组,将86例盖诺化疗患者分为实验组和对照组各43例,对实验组患者采用化疗前后生理盐水100 m l加地塞米松10 mg滴注冲洗静脉,另加新鲜芦荟外敷穿刺静脉。对照组按一般化疗进行。结果两组静脉炎的发生率实验组41.9%(18/43),对照组81.4%(35/43),两组差别具有显著性意义(Hc=18.01,P<0.00002)。结论对盖诺化疗采取保护措施,可减轻其对血管的刺激,减少静脉炎的发生。

The Effect Observatirn of Dexamethasone Plus Aloe Vera Applying to Prevent the Vein Injury by Vinorelbire-chemotherapy

Objective To evaluate the effect of prophyiactic protective methods for vein in 86 patients treated with vinorelbin.Methods 86 Patients with vinorelbine-chemotherapy were recruited in this study,who were randomly divided into control group and experimental group.Every group included 43 cases respectively.The experimental group received venoclysis of 0.9% Natvii chloride 100 ml and Dexamethasone 10mg fore-and postchemotherapy to clear the vein,at the same time,the fresh Aloe Vera was applied externally to protect the punctured vein.While the cases of control group received common treatment and care.Results Of 43 experimental group patients,18(41.9%) developed vasculitis.Otherwise,35(81.4%) patients in the control group had occurred the vasculitis.The experimental group had less morbidity.(Hc=18.01,P<0.00002).Conclusion The prophy lactic protective approaches for vinorelbine-treated patients can alleviate the harm of the vein,and reduced the incidence rate of the vasculitis.