| 病毒性心肌炎引起心肌纤维化机制探讨 |
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| 引用本文： | 韩奇杰,罗斌,马艺列,刘水平,唐双柏,阳宇,程灵犀,江东华,孔小平. 病毒性心肌炎引起心肌纤维化机制探讨[J]. 国外医学:内科学分册, 2009, 36(9): 512-515,523 |
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| 作者姓名： | 韩奇杰 罗斌 马艺列 刘水平 唐双柏 阳宇 程灵犀 江东华 孔小平 |
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| 作者单位： | 中山大学基础医学院法医学系,广州,510080;广州市公安局萝岗区分局,广州,510760;上海市检察院,上海,200030;广州市公安局番禺区分局,广州,511400 |
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| 基金项目： | 国家自然科学基金，广东省医学科研基金 |
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| 摘 要： | 病毒性心肌炎是一种常见的感染性疾病，在急性期常因起病隐匿而以猝死为首要表现；恢复期和慢性期则伴有明显的心肌纤维化，部分患者最后进展为扩张型心肌病和严重的充血性心力衰竭。多种因素参与心肌纤维化，本文就这些影响因素的相互作用及如何调控纤维化的发生发展机制作一综述，为临床上心肌炎的防治提供理论依据。
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| 关 键 词： | 病毒性心肌炎 心肌纤维化 心肌胶原网络 |
Discussion on mechanism reponsible for myocardial fibrosis in viral myocarditis |
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| HAN Qi-jie,LUO Bin,MA Yi-lie,LIU Shui-ping,TANG Shuang-bo,YAVG Yu,CHENG Ling-xi,JIANG Dong-hua,KONG Xiao-ping. Discussion on mechanism reponsible for myocardial fibrosis in viral myocarditis[J]. Foreign Medical Sciences(Section of Internal Medicine), 2009, 36(9): 512-515,523 |
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| Authors: | HAN Qi-jie LUO Bin MA Yi-lie LIU Shui-ping TANG Shuang-bo YAVG Yu CHENG Ling-xi JIANG Dong-hua KONG Xiao-ping |
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| Affiliation: | HAN Qi-jie1,LUO Bin1,MA Yi-lie2,LIU Shui-ping,TANG Shuang-bo,YAVG Yu,CHENG Ling-xi,JIANG Dong-hua,KONG Xiao-ping. Department of Forensic Pathology,Zhongshan Medical School,Sun Yat-sen University,Guangzhou 510080,China |
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| Abstract: | Viral myocarditis is a common infectious disease,which always appeared as sudden unexpected natural death for its hiding onset.The heart of patients always had a fibrosis at the recovery or chronic period.Some people developed into dilated cardiomyopathy at last.This article reviewed present progression of the cardiac collagen net-work(CCN),changes of the CCN in viral myocarditis and the influence factors. |
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| Keywords: | Viral myocarditis Myocardial fibrosis Cardiac collagen net-work |
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