| 产后康口服液质量标准研究 |
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| 引用本文： | 储秋萍,朱子寒.产后康口服液质量标准研究[J].中国药事,2009,23(4):362-364. |
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| 作者姓名： | 储秋萍 朱子寒 |
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| 作者单位： | 南京医科大学第一附属医院,南京,210029 |
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| 摘 要： | 目的建立产后康口服液的质量控制标准。方法采用薄层色谱法对制剂中的当归、川芎、益母草进行定性鉴别;采用高效液相色谱法对阿魏酸进行含量测定。色谱柱为Hypersil ODS柱;流动相：甲醇-5%醋酸（25∶75）,流速：1.0 mL·min^-1;检测波长：320nm。结果阿魏酸线性范围在0.167～1.668μg（r=0.9996）;平均回收率为98.55%,RSD=1.69%（n=9）。结论方法简便、准确、重复性好,可用于产后康口服液质量控制。
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| 关 键 词： | 产后康口服液 阿魏酸 质量标准 |
Study on the Quality Standard of Chanhoukang Oral Liquid |
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| Chu Qiuping,Zhu Zihan.Study on the Quality Standard of Chanhoukang Oral Liquid[J].Chinese Pharmaceutical Affairs,2009,23(4):362-364. |
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| Authors: | Chu Qiuping Zhu Zihan |
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| Institution: | Chu Qiuping and Zhu Zihan (First Affiliated Hospital Nanjing Medical University, Nanjing 210029) |
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| Abstract: | Objective To establish a quality standard for Chanhoukang Oral Liquid. Methods TLC was used to identify Radix Angelicae Sinensis, Rhizoma Chuanxiong and Herba Leonari. HPLC method for the determination of ferulic acid in Chanhoukang Oral Liquid was established. The separation was performed on Hypersil ODS column, using with methanol-5%HAc （25： 75） as mobile phase, the flow rate was 1.0 mL·min^-1 , the detection wave length was 320nm. Results The calibration curve was linear in the range of 0. 167-1. 668μg （r=0. 9996）. The average recovery was 98. 55%, RSD=1. 69 % （n=9）. Conclusions The method is simple and accurate and highly reproducible. It could be used for the quality control of Chanhoukang Oral Liquid. |
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| Keywords: | Chanhoukang Oral Liquid ferulic acid quality standard |
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