Flavanone glycosides from Miconia trailii |
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| Authors: | Zhang Zhizhen ElSohly Hala N Li Xing-Cong Khan Shabana I Broedel Sheldon E Raulli Robert E Cihlar Ronald L Walker Larry A |
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| Institution: | National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, and Department of Pharmacology, School of Pharmacy, University of Mississippi, University, Mississippi 38677, USA. |
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| Abstract: | Assay-guided fractionation of the ethanol extract of the twigs and leaves of Miconia trailii yielded two new flavanone glycosides, matteucinol 7-O-alpha-l-arabinopyranosyl(1-->6)-beta-d-glucopyranoside (miconioside A, 1) and farrerol 7-O-beta-d-apiofuranosyl(1-->6)-beta-d-glucopyranoside (miconioside B, 2), along with the known compounds matteucinol 7-O-beta-d-apiofuranosyl(1-->6)-beta-d-glucopyranoside (3), matteucinol (4), 2alpha,3beta,19alpha-trihydroxyolean-12-ene-24,28-dioic acid (bartogenic acid, 5), 2alpha,3beta,23-trihydroxyolean-12-ene-28-oic acid (arjunolic acid, 6), 2alpha,3alpha,19alpha, 23-tetrahydroxyurs-12-ene-28-oic acid (myrianthic acid, 7), and stigmast-4-ene-3,6-dione (8). The structures of 1-8 were elucidated by spectroscopic methods, including 2D NMR. |
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