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乙型肝炎疫苗致不良反应72例文献分析
引用本文:王川平,殷立新,姚玉兰. 乙型肝炎疫苗致不良反应72例文献分析[J]. 中国药房, 2005, 16(16): 1250-1251
作者姓名:王川平  殷立新  姚玉兰
作者单位:河北医科大学第二医院药科,石家庄市,050000
摘    要:目的:探讨乙型肝炎疫苗致不良反应的一般规律及特点。方法:对近10年国内报道的使用乙型肝炎疫苗致不良反应72例进行分类统计、分析。结果:不良反应多发生于1a~40a年龄组,且男性多于女性;多于用药后30min内发生;不良反应临床表现为变态反应,严重者可出现过敏性休克。结论:临床应重视乙型肝炎疫苗所致的不良反应,确保用药安全。

关 键 词:乙型肝炎疫苗  药品不良反应  文献分析
文章编号:1001-0408(2005)16-1250-02
收稿时间:2005-04-27
修稿时间:2005-04-27

Literature Analysis on 72 Cases of Adverse Drug Reactions Caused by Hepatitis B Vaccine
Wang Chuanping,Yin Lixin,YAO Yulan. Literature Analysis on 72 Cases of Adverse Drug Reactions Caused by Hepatitis B Vaccine[J]. China Pharmacy, 2005, 16(16): 1250-1251
Authors:Wang Chuanping  Yin Lixin  YAO Yulan
Abstract:OBJECTIVE:To analyze the general features of adverse drug reactions(ADRs)caused by hepatitis B vaccine.METHODS:72national case reports of ADRs induced by hepatitis B vaccine in recent10years were classified and analyzed statistically.RESULTS:The affected patients ranged in age from1year to 40 years,with more males than females;Most ADRs occurred with in 30 minutes after the medication;The ADRs were characterized by allergies in clinic,even allergic shock.CONCLUSIONS:It is important to manage the ADRs caused by hepatitis B vaccine for the safety of medication.
Keywords:Hepatitis B vaccine  Adverse drug reaction  Literature analysis
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