针刺联合中药治疗功能性消化不良临床观察

目的观察针刺联合中药治疗功能性消化不良患者的疗效及对消化功能的影响。方法回顾性分析2015年8月至2017年8月收治的功能性消化不良患者68例为研究对象,根据患者所采用的治疗方案不同分为观察组和对照组,对照组(33例)采用中药治疗,观察组(35例)采用针刺联合中药治疗。比较两组患者的临床疗效、治疗前后消化不良症状评分、胃排空变化以及血清中胃动素和神经肽水平的差异。结果观察组总有效率(85.7%)明显优于对照组(63.6%),两组比较差异有统计学意义(P<0.05);观察组治疗前饱胀不适、早饱感、上腹痛、上腹烧灼感评分与对照组比较差异无统计学意义(P>0.05),观察组治疗后上述各消化不良症状评分均明显低于对照组(P<0.05);两组治疗前胃排空情况相比无明显差异(P>0.05),观察组治疗后胃排空情况明显优于对照组(P<0.05);观察组治疗前血清胃动素、神经肽水平与对照组比较差异无统计学意义(P>0.05),观察组治疗后血清胃动素、神经肽水平均明显高于对照组(P<0.05)。结论针刺联合中药治疗功能性消化不良,可有效提高患者血清中胃动素和神经肽水平,促进胃排空,改善其消化不良的症状,提高胃肠动力。

Clinical Observation of Acupuncture plus Chinese Medication for Functional Dyspepsia

Objective To observe the effect of acupuncture plus Chinese medication on the therapeutic efficacy and digestive function in treating patients with functional dyspepsia(FD).Method A retrospective analysis was carried out by targeting 68 FD patients admitted during August 2015 and August 2017.According to the treatment protocol the patients received,they were divided into an observation group and a control group.The control group(33 cases)received Chinese medication,and the observation group(35 cases)was intervened by acupuncture plus Chinese medication.The two groups were compared in terms of clinical efficacy,and post-treatment changes in dyspepsia symptom score,gastric emptying,and the levels of motilin and neuropeptide in serum.Result The total effective rate in the observation group(85.7%)was higher than that in the control group(63.6%),and the difference was statistically significant(P<0.05);before treatment,there were no significant differences between the two groups in the scores of bloating discomfort,early satiation,upper abdominal pain,and upper abdominal burning sensation(P >0.05),while the scores of the dyspepsia symptoms mentioned above were significantly lower in the observation group than in the control group after treatment(P<0.05);there was no significant difference in gastric emptying between the two groups before treatment(P >0.05),while the gastric emptying evaluation was better in the observation group than in the control group after treatment(P<0.05);the between-group differences in the serum levels of motilin and neuropeptide were statistically insignificant before treatment(P >0.05),while the levels of motilin and neuropeptide in serum of the observation group were significantly higher than those in the control group after treatment(P<0.05).Conclusion Acupuncture plus Chinese medication can effectively increase the levels of motilin and neuropeptide in serum,boost gastric emptying,and improve dyspepsia symptoms and gastrointestinal motility in treating FD.