电针联合西药对颈性眩晕患者血液理化的影响

目的观察电针联合盐酸氟桂利嗪胶囊对颈性眩晕患者血液理化性质影响。方法 118例颈性眩晕患者随机分成观察组和对照组,每组59例。对照组给予口服盐酸倍他司汀片和盐酸氟桂利嗪胶囊,观察组在对照组基础上行电针治疗。观察两组治疗前后患者眩晕、颈肩痛及头痛积分变化,采用经颅多谱勒超声仪(TCD)测量时间平均血流速度(TAMn)、收缩期最大血流速度(PS),ELISA法检测血清降钙素基因相关肽(CGRP)、D-二聚体(DD)及内皮素-1(ET-1)含量,并比较两组临床疗效。结果观察组总的有效率为93.2%,对照组为74.6%,两组比较差异有统计学意义(P<0.05)。观察组治疗后眩晕、头痛及颈肩痛临床评分较治疗前、对照组显著降低,差异有统计学意义(P<0.05)。观察组治疗后基底动脉、左侧椎动脉及右侧椎动脉PS,基底动脉TAMn较治疗前、对照组显著上升,差异有统计学意义(P<0.05)。观察组治疗后血清CGRP含量较治疗前、对照组上升,DD、ET-1含量较治疗前、对照组下降,差异均有统计学意义(P<0.05)。结论电针联合西药可显著改善颈性眩晕患者血液理化性质异常和椎-基底动脉供血不足,疗效显著。

Effect of Electroacupuncture plus Western Medication on Blood Physiochemical Parameters in Cervical Vertigo Patients

Objective To observe the effect of electroacupuncture plus flunarizine hydrochloride capsules on blood physiochemical properties in cervical vertigo patients. Method A total of 118 patients with cervical vertigo were randomized into an observation group and a control group, with 59 cases in each group. The control group was given oral administration of betahistine hydrochloride tablets and flunarizine hydrochloride capsules, while the observation group was additionally given electroacupuncture. The scores of vertigo, neck-shoulder pain and headache were observed before and after treatment in the two groups. Transcranial Doppler was used to detect the time averaged maximum velocity (TAMn) and peak systolic blood flow velocity (PS);enzyme-linked immunosorbent assay (ELISA) was used to examine the contents of calcitonin gene-related peptide (CGRP), D-dimer (DD) and endothelin (ET)-1. The clinical efficacies of the two groups were also compared. Result The total effective rate was 93.2% in the observation group versus 74.6% in the control group, and the difference was statistically significant (P<0.05). The scores of vertigo, headache and neck-shoulder pain in the observation group decreased significantly after the intervention and were significantly lower compared with those in the control group (P<0.05). The PS values of basilar and vertebral arteries and TAMn of the basilar arteries in the observation group increased significantly after the intervention and were significantly higher than those in the control group (P<0.05). The serum content of CGRP in the observation group increased significantly after treatment and was markedly higher than that in the control group, and the contents of DD and ET-1 in the observation group decreased significantly after treatment and were significantly lower than those in the control group (P<0.05). Conclusion Electroacupuncture plus Western medication can obviously improve the abnormal blood physiochemical parameters and vertebrobasilar insufficiency in cervical vertigo patients, and the efficacy is significant.