穴位贴敷防治支气管哮喘的疗效观察

目的观察穴位贴敷防治支气管哮喘的临床疗效及穴位贴敷后皮肤反应情况。方法将60例支气管哮喘患者随机分为治疗组和对照组,每组30例。两组均于三伏天初、中、末伏的前3 d在肺俞、心俞、膈俞的对照穴位上进行低剂量药物穴位贴敷治疗,对照组次年在相同时间进行相同治疗,治疗组次年于三伏天初、中、末伏的前3 d在肺俞、心俞、膈俞穴上进行常规剂量药物穴位贴敷治疗。观察两组治疗前后哮喘发作次数、肺功能各项指标[最大呼气中期流量(maximum mid-expiratory flow, MMEF)、用力呼气25%肺活量的瞬间流速(forced expiratory flow at 25% of the pulmonary volume, FEF25%)、用力呼气50%肺活量的瞬间流速(FEF50%)及用力呼气75%肺活量的瞬间流速(FEF75%)]及贴敷后皮肤反应情况。结果治疗组治疗2年后哮喘发作次数与治疗前比较,差异具有统计学意义(P<0.05)。治疗组治疗2年后肺功能各项指标与治疗前及治疗1年后比较,差异均具有统计学意义(P<0.05)。两组治疗2年后肺功能各项指标及皮肤反应比较,差异均具有统计学意义(P<0.05)。结论穴位贴敷能有效改善哮喘患者的小气道功能,从而减少哮喘的发作,其疗效与贴敷后出现皮肤反应可能相关。

Observation on the Efficacy of Acupoint Application in Preventing and Treating Bronchial Asthma

Objective To observe the clinical efficacy of acupoint application in preventing and treating bronchial asthma and the skin reaction after acupoint application. Method Sixty patients with bronchial asthma were randomized into treatment and control groups, with 30 cases in each group. Both groups were intervened by acupoint application at the control acupoints of Feishu (BL13), Xinshu (BL15) and Geshu (BL17) with low-dose medication three days during the first, second and last of the three periods of the hot season. The control group was intervened by the same treatment at the same time in the next year, while the treatment group was intervened by acupoint application at Feishu (BL13), Xinshu (BL15) and Geshu (BL17) with regular-dose medication. The number of asthma attack, indicators of lung function [maximum mid-expiratory flow (MMEF), forced expiratory flow at 25% of the pulmonary volume (FEF25%), FEF50% and FEF75%] and the skin reaction after acupoint application in the two groups were observed before and at the end of the treatment. Result After two-year treatment, the number of asthma attack in the treatment group was significantly different from that before the treatment (P<0.05). After two-year treatment, the indicators of lung function in the treatment group were significantly different from those before the treatment or after one-year treatment (P<0.05). After two-year treatment, the indicators of lung function and the skin reaction after acupoint application in the treatment group were significantly different from those in the control group (P<0.05). Conclusion Acupoint application can effectively improve small airway function in the patients with bronchial asthma, and therefore reduce asthma attacks. The efficacy is possibly related to the skin reaction after acupoint application.