| HPLC法测定尿清颗粒中丹参酮ⅡA的含量 |
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| 引用本文： | 刘文启. HPLC法测定尿清颗粒中丹参酮ⅡA的含量[J]. 齐鲁药事, 2007, 26(2): 86-88 |
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| 作者姓名： | 刘文启 |
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| 作者单位： | 临沂市人民医院,临沂,276003 |
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| 摘 要： | 目的建立尿清颗粒中丹参酮ⅡA的含量测定方法。方法采用HPLC法,KromasilC18(250mm×4.6mm,5μm)色谱柱,流动相:甲醇-水(75∶25),检测波长:270nm,流速:1ml.min-1。结果丹参酮ⅡA线性范围为0.528～2.64μg,回收率(n=6)为99.14%,RSD=1.37%。结论本方法分离效果好,准确可靠,是控制尿清颗粒内在质量的有效方法。
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| 关 键 词： | HPLC 尿清颗粒 丹参酮ⅡA 含量测定 |
| 文章编号： | 1672-7738(2007)02-0086-03 |
Determination of tanshinone IIA in Niaoqing Granules by HPLC |
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| LIU Wen-qi. Determination of tanshinone IIA in Niaoqing Granules by HPLC[J]. qilu pharmaceutical affairs, 2007, 26(2): 86-88 |
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| Authors: | LIU Wen-qi |
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| Abstract: | OBJECTIVE To establish the determination of tanshinone IIA in Niaoqing Granules.METHODS HPLC method was developed for the determination of tanshinone IIA in Niaoqing Granules on Kromasil C18(250mm×4.6mm,5μm),using methane-water(75∶25,v:v)as mobile phase(1.0ml·min-1)and detection wavelength was 270nm.RESULTS The linear range of tanshinone IIA was 0.528～ 2.64μg and the correlation coefficient was 0.9999,the average recovery was 99.14%,RSD was 1.37%(n=6).CONCLUSION The method was convenient and accurate.It can be used for the quality control of Niaoqing Granules. |
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| Keywords: | HPLC |
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