自体角膜缘干细胞移植术治疗翼状胬肉43例临床观察

目的 评价自体角膜缘干细胞移植术治疗翼状胬肉的疗效。方法采用自体角膜缘干细胞移植术治疗54眼(43例)翼状胬肉，其中原发性翼状胬肉38眼，复发性翼状胬肉16眼。16眼复发性胬肉均经过两次以上的单纯胬肉切除术或结膜下转移术。结果 术后随访6-18个月，无术后并发症发生。49眼无胬肉组织再生，5眼在术后8—11个月复发，复发率为9．3％。结论 自体角膜缘干细胞移植术能为受损的角膜缘提供新的干细胞，是一种安全、有应用前景的治疗翼状胬肉的手术方式。

Clinical Observation of Corneal Limbal Stem Cell Autograft Transplantation in Treatment of Pterygium

Objective To assess the therapeutic effects of corneal limbal stem cell autograft transplantation for the treatment of pterygium. Methods Corneal limbal stem cell autograft transplantation were performed on 54 eyes(43 cases) with newly developed(n=38) or recurrent pterygium(n=16). All the recurrent pterygium had already been treated at least twice either by simple excision (n=11) or by conjunctival rotation autograft (n=5).Results During 6-18 months of follow-up no postoperative complications occurred. In 49 eyes no pterygium recurrence was recorded; recurrence occurred in 5 eyes (9.3%) after 8 to 11 months. Conclusion Corneal limbal stem cell autograft transplantation can provide new stem cells for the damaged limbal,it seems to be a promising and safe procedure for pterygium.