| 西拉普利与美托洛尔对高血压前臂动脉功能影响的临床研究 |
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| 引用本文： | 王占成,朱满芳,舒怡和,徐律,舒志萍,张维忠,龚兰生.西拉普利与美托洛尔对高血压前臂动脉功能影响的临床研究[J].中华高血压杂志,2001,9(1):27-29. |
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| 作者姓名： | 王占成 朱满芳 舒怡和 徐律 舒志萍 张维忠 龚兰生 |
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| 作者单位： | 1. 上海邮电医院内科
2. 上海市高血压研究所 |
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| 摘 要： | 目的比较西拉普利与美托洛尔长期治疗对原发性高血压患者肱动脉功能的影响。
方法脉冲多普勒法。
结果两组原发性高血压患者分别接受西拉普利或美托洛尔治疗6个月后血压均明显下降，但西拉普利组的肱动脉管径、血流速度、血流量和扩张性增加，血流阻力减少；而美托洛尔治疗组的肱动脉管径、血流速度、血流量和扩张性有所下降或无明显改变。
结论西拉普利可以部分改善高血压患者前臂动脉功能
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| 关 键 词： | 原发性高血压 肱动脉 超声 西拉普利 美托洛尔 |
| 文章编号： | 1006-2866(2001)02-0027-02 |
| 修稿时间： | 2000年4月24日 |
Effect of Cilazapril and Metoprolol on Brachial Artery in Patients with Essential Hypertension |
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| WANG Zhan-cheng,ZHU Man-fang,SHU Yi-he,XU Lu,SHU Zhi-ping,ZHANG Wei-zhong,GONG Lan-sheng.Effect of Cilazapril and Metoprolol on Brachial Artery in Patients with Essential Hypertension[J].Chinese Journal of Hypertension,2001,9(1):27-29. |
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| Authors: | WANG Zhan-cheng ZHU Man-fang SHU Yi-he XU Lu SHU Zhi-ping ZHANG Wei-zhong GONG Lan-sheng |
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| Abstract: | Aim:To compare the effect of cilazapril and metoprolol on the compliance o f brachial artery in essential hypertension(EH).
Methods:Compliance of brachial artery was determined by Pulsed Doppl er techniques. Brachial artery diameter(Dd),flow velocity(Vm),volumic blood flow (Q) and the distensibility(Dis) increased markedly,the resistance(R) used as the indexes of compliance of brachial artery.
Results:Sixty seven EH were divided into two groups(A,B) random ly. Group A were treated with Cilazaril,Group B with Metoprolol. Aft er 6 months treatment, BP in all the patients decreased. In Group A,the Dd,Vm,Q and Dis increased markedly,but R of brachial artery decreased obviously. In group B,no obvious changes of branchial artery were found.
Conclusion:Cilazapril may improve the compliance of brachial artery partially. |
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