骨组织工程支架材料的种类及发展趋势*

摘要：组织工程支架材料不仅在细胞黏附、增殖和新骨组织形成中为细胞提供结构支撑，而且还起到模板作用，引导组织再生和控制组织结构。寻找一种既有良好生物相容性和生物降解性又具有特定形状的支架材料是骨组织工程的一个重要方面。文章对用于骨组织工程支架材料的天然高分子材料、人工合成聚合物及无机材料及复合材料等的研究现状进行探讨，并分析这些材料的优缺点及骨组织工程支架材料的发展趋势。

Type and progress of bone tissue engineering scaffold materials

Abstract: The tissue engineering scaffold materials provide not only a structural support for cell adhesion, proliferation, and new bone formation, but also play a template role in guiding tissue regeneration and controlling tissue structure. Looking for a scaffold material with good biocompatibility, biodegradability, and specific shape is importance for bone tissue engineering research. This article was designed to explore natural polymer materials, artificial synthetic polymer materials, inorganic materials, and composite materials, to analyze the advantages and disadvantages of those materials, and to predict the developing tendency of bone tissue engineering scaffold materials.