伊曲康唑间隙冲击疗法治疗甲真菌病200例

目的 :观察伊曲康唑冲击疗法治疗甲真菌病的临床疗效。方法 :2 0 0例甲真菌病患者每天口服伊曲康唑胶囊 2次 ,每次 2 0 0mg× 7天 ,停药 2 1天为 1个疗程。指甲真菌病用药 2个疗程 ,趾甲真菌病及指趾甲真菌病用药 3个疗程。结果 82例指甲真菌病临床痊愈率 91 4 6 % ,118例趾甲真菌病及指趾甲同患真菌病临床痊愈率 81 36 % ,二者伴发皮肤真菌感染者真菌清除率分别为 98 5 %和 97%。结论 :伊曲康唑短期冲击疗法治疗甲真菌病疗程短、疗效高、副作用小、安全性高、复发率低。

Treatment of onychomycosis by pulse usage of itraconazole

Objective To observe the curative effect in the treatment of onychomycosis with itraconazole pulse therapy.Method Total patients were 200.The course of treatment was to take orally itraconazole capsule twice every day,each time 200mg for 7 days and to stop taking it for 21 days.For fingernail onychomycosis 2 courses were needed,and for toenail onychomycosis 3 courses.Results The cure rate of onychomycosis was 91.46% in 82 patients with fingernail onychomycosis and 81.36% in 118 patients with toenail and both fingernail and toenail onychomycosis.The fungal infection clearance rates were 98.5% and 97% respectively in the patients with fingernail and toenail onychomycosis.Conclusions Itraconazole short-phase therapy is a high-efficient,small side-effect,high safety and low recurrent therapy for onychomycosis.