| 六味地黄汤活性部位3A的免疫调节作用研究 |
| |
| 引用本文： | 杨胜,张永祥,吕晓东,董剑英,乔善义,赵毅民. 六味地黄汤活性部位3A的免疫调节作用研究[J]. 中草药, 2001, 32(4): 326-329 |
| |
| 作者姓名： | 杨胜 张永祥 吕晓东 董剑英 乔善义 赵毅民 |
| |
| 作者单位： | 军事医学科学院毒物药物研究所，北京 100850 |
| |
| 基金项目： | 国家重点基础研究发展规划项目 !( No G19990 5 440 1)，“九·五”国家攀登计划预选项目!资助课题 |
| |
| 摘 要： | 目的：初步研究六味地黄汤活性部位3A的免疫调节作用，方法：观察po给予3A对环磷酰胺（Cy)处理小鼠，肉瘤S180荷瘤小鼠及快速老化模型小鼠（SAM）等免疫功能低下模型免疫反应的影响。结果：3A对以上模型低下的抗体生成反应和脾细胞增殖反应具有明显的改善作用。结论：3A具有明显的免疫调节作用。 六味地黄汤的重要活性部位之一。
|
| 关 键 词： | 六味地黄汤 活性部位 3A 免疫调节 小鼠 |
| 收稿时间： | 2000-08-07 |
Studies on immunomodulatory activity of fraction 3A from LIUWEIDIHUANG DECOCTION |
| |
| YANG Sheng,ZHANG Yongxiang,LV Xiaodong,DONG Jianying,QIAO Shanyi and ZHAO Yimin. Studies on immunomodulatory activity of fraction 3A from LIUWEIDIHUANG DECOCTION[J]. Chinese Traditional and Herbal Drugs, 2001, 32(4): 326-329 |
| |
| Authors: | YANG Sheng ZHANG Yongxiang LV Xiaodong DONG Jianying QIAO Shanyi ZHAO Yimin |
| |
| Affiliation: | Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850, China;Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850, China;Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850, China;Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850, China;Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850, China;Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850, China |
| |
| Abstract: | Object To carry out a preliminary investigation on the immunomodulatory activity of fraction 3A, a fraction from the ethanol soluble portion of LIUWEIDIHUANG DECOCTION (LW) * Methods Effects of fraction 3A (po) on antibody production response and splenocyte proliferation of models with cyclophosphamid treated, sarcoma S 180 bearing and senescence accelerated mouse prone/8 (SAMP8) mice were evaluated Results Fraction 3A (po) significantly improved the immune response in all of the immunodeficient models Conclusion Fraction 3A possesses potent immunomodulating effect and is one of the important effective fraction of LW |
| |
| Keywords: | LIUWEIDIHUANG DECOCTION (LW) effective fraction 3A immunomodulation |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《中草药》浏览原始摘要信息 |
|
点击此处可从《中草药》下载全文 |
|
