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| 牛膝多糖对小鼠红细胞免疫功能的影响 | |
| 引用本文： | 邵树军,买玲,陈瑛. 牛膝多糖对小鼠红细胞免疫功能的影响[J]. 中国药物与临床, 2002, 2(5): 281-282 |
| 作者姓名： | 邵树军 买玲 陈瑛 |
| 作者单位： | 1. 河南省肿瘤研究所药化免疫室,450003 2. 河南省肿瘤研究所细胞生物室,450003 3. 河南省胸科医院内科 |
| 基金项目： | 河南省自然科学基础研究基金资助项目 |
| 摘 要： | 目的 探讨牛膝多糖 (ABP)对正常及免疫低下小鼠红细胞免疫功能的影响。方法 ABP经腹腔注射给药后 ,测定各组小鼠外周血中红细胞C3b受体及红细胞粘附免疫复合物花环结合率的变化。结果 ABP 6 0mg·kg-1·d-1,10d能显著提高正常及免疫低下小鼠红细胞C3b受体花环结合率和红细胞粘附免疫复合物花环结合率。结论 ABP是一种免疫调节剂 ,能提高正常及免疫低下小鼠的红细胞免疫功能 |
| 关 键 词： | 牛膝多糖 免疫功能 C3b受体 免疫复合物 |
| 修稿时间： | 2002-05-30 |
The effect of achyranthes bidentata polysaccharide on mice red blood cell immunological function |
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| Abstract: | Objective To study the effect of achyranthes bidentata polysaccharide (ABP) on RBC immunolgical function in normal and immunosuppressed mice.Methods The red blood cell C3b receptor rate (C3bRR) and immune complex rate (ICR) in peripheral blood were measured after intraperitoneal injection of ABP in normal and immunosuppressed mice. Results ABP 60 mg·kg -1·d -1 10 d significantly increased C3bRR and ICR in immunosuppressed and normal mice peripheral blood.Conclusion It was suggested that ABP was a kind of immunomodulator,and could improve the RBC immunological function of normal and immunosuppressed mice. |
| Keywords: | Achyranthes bidentata polysaccharide Immunological function C3b receptor Immune complex |
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