腰2交感神经节毁损治疗癌性腰腿痛的效果观察

目的探讨腰2交感神经节毁损术治疗癌性腰腿痛的临床疗效.方法癌性腰腿痛患者50例,在数字减影机数字减影血管造影(DSA)下用无水酒精行腰2交感神经节毁损术,对治疗前、治疗后7d、30d、90d分别行视觉模拟(VAS)及生活质量评分,并观察术中及术后并发症的发生率.结果与治疗前比较,治疗后7d、30d及90d的VAS评分明显降低,差异有统计学意义(P<0.05),VAS评分相互比较,无统计学差异(P>0.05).与治疗前比较,治疗后7d、30d及90d的生活质量评分明显降低,差异有统计学意义(P<0.05),生活质量评分相互比较,无统计学差异(P>0.05).50例癌性腰腿痛患者中,术后出现腰痛7例,发生率14%,神经损伤2例,发生率4%.未发生腰动脉、生殖股神经痛、肾脏损伤及蛛网膜下腔阻滞等并发症.结论腰2交感神经节毁损术治疗癌性腰腿痛有较好的临床疗效.

Lumbar sympathetic ganglion damage 2 in treatment of cancer pain effect

Objective 50 cases of lumbar 2 sympathetic ganglia lesion for the treatment of cancer pain clinical. Methods of cancer patients with lumbocrural pain, reducing digital camera in digital subtraction angiography（DSA） with anhydrous alcohol lumbar sympathetic ganglion neurolysis in 2, before and after the treatment, 7 days, 30 days, 90 days respectively, visual simulation （VAS） and life quality score. Results Compared with before treatment and to observe the intraoperative and postoperative complications, 7 days after treatment, 30 days and 90 days of VAS score decreased significantly, the difference was statistically significant（P〈0.05）~ after treatment for 7 days, 30 days and 90 days of VAS score compared with each other, no significant difference（P〉0.05）. Compared with before treatment, 7 days after treatment, 30 days and 90 days of the quality of life score decreased significantly, the difference was statistically significant（P〈O.05）~ 7 days after treatment, 30 days and 90 days of the quality of life score compared with each other, no significant difference（P〉0.05）. 50 cases of cancer patients with lumbocrural pain, postoperative pain in 7 cases, the incidence was 14%, 2 cases of nerve injury, the incidence was 4%. Without the occurrence of lumbar artery, genitofemoral nerve pain, renal injury and subarachnoid anesthesia complications. Conclusion The 2 lumbar sympathetic ganglion damage has good clinical curative effect in the treatment of cancer pain.