| 血清fPSA与tPSA比值对鉴别诊断前列腺癌的价值 |
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| 引用本文： | 季广厚. 血清fPSA与tPSA比值对鉴别诊断前列腺癌的价值[J]. 中国医疗前沿, 2013, 0(14): 100-101 |
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| 作者姓名： | 季广厚 |
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| 作者单位： | 273200,山东省济宁市泗水县人民医院检验科 |
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| 摘 要： | 目的研究游离前列腺特异性抗原(fPSA)及总前列腺特异性抗原(tPSA)的比值(f/tPSA)对前列腺癌(PCa)鉴别诊断的价值。方法检测fPSA与tPSA并算出比值f/tPSA；同时算出不同f/tPSA所对应的特异性和敏感性。结果在4-10ng/ml的诊断灰区，PCa组与前列腺增生(BPH)组间血清中fPSA和tPSA的水平均无显著差异，而f/tPSA比值，PCa组(0.12±0.05)和BPH组(0.28±0.09)间差异显著(P<0.001)。结论在诊断灰区对前列腺癌的鉴别诊断，用f/tPSA比值比单独用tPSA及fPSA更有价值，诊断鉴别点以f/tPSA<0.19较为合适。
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| 关 键 词： | f/tPSA 诊断灰区 前列腺癌 |
The Differential and Diagnostic Value for Prostate Cancer of the Serum Free PSA and Total PSA Ratio |
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| JIGuang-hou. The Differential and Diagnostic Value for Prostate Cancer of the Serum Free PSA and Total PSA Ratio[J]. China Healthcare Innovation, 2013, 0(14): 100-101 |
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| Authors: | JIGuang-hou |
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| Affiliation: | JI Guang- , hou. Department of Mecfl＇cal Laboratory, People＇s Hospital of Sishui County, Jining 273200, China |
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| Abstract: | Objective Research on the differential diagnostic value for prostate cancer（Pea） of the free PSA and total PSA ratio. Methods Detection of fPSA and tPSA and calculation of the ratio and Calculates of the correspondent sensitivity and specificity of different f/tPSA. Results There is no significant difference between Pca group and BPH group in fPSA and tPSA, on the contrary, there is very significant difference between Pca group（0.12±0.05） and BPH group（0.28±0.09） in f/tPSA（P〈0.001） in the diagnoses gray zone between 4-10ng/ml. Conclusion In the diagnoses gray zone, it is more effective to differentiate diagnose prostate cancer by means of f/tPSA ratio than by means of tPSA and fPSA, and it is more suitable to treat f/tPSA〈0.19 as the diagnosis differentiation spot. |
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| Keywords: | f/tPSA Diagnoses Gray Zone Prostate Cancer |
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