解剖性肝切除联合脾切除对肝癌合并门脉高压、脾亢治疗效果的临床观察

目的观察解剖性肝切除联合脾切除对肝癌合并门脉高压症并脾亢的疗效,探讨其临床意义。方法将我院确诊为原发性肝癌合并门脉高压症并脾亢的80例患者随机分为两组各40例,观察组应用解剖性肝切除联合脾切除进行治疗,对照组应用传统非解剖性肝切除联合脾切除进行治疗。结果两组患者均顺利完成手术,观察组患者术中出血量及围手术期的输血量明显低于对照组,脾亢改善情况、术后2年生存率较对照组明显提高,术后2年生活质量明显高于对照组。结论解剖性肝切除联合脾切除对原发性肝癌合并门脉高压症并脾亢患者的治疗效果理想,可提高患者术后生存率及生活质量。

The clinical observationon anatomical hepatic resection combined with splenectomy in patients with primary hepotocm/lular carcinoma, portal hylrtension and hypersplenism

Objective To study the clinical effect of anatomical hepatic resection combined with splenectomy surgery in patients with primary hepatocellular carcinoma, portal hypertension and hypersplenism. Methods 80 cases with primary hepatocellular carcinoma, portal hypertension and hypersplenism were observed and divided into two groups. The control group（40 cases） were treated by traditional hepatic resection and splenectomy, the observation group（40 cases） were treated by anatomical hepatic resection combined with splenectomy. Results All procedures were completed successfully in two groups. The intraoperative blood loss and transfusion volume in the observation group were less than in the control group. The hypersplenism were improved in two groups. The survival rate and life quality in the observation group were higher than in the control group. Conclusion The surgery treatment of anatomical hepatic resection combined with splenectomy can increase the clinical efficiency, improve the survival rate and life quality in patients with hepatocellular carcinoma, portal hypertension and hypersplenism.