| 脑血栓患者血清IL-10水平及其临床意义 |
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| 引用本文： | 刘富东,储照虎,吴家幂,张新路. 脑血栓患者血清IL-10水平及其临床意义[J]. 放射免疫学杂志, 2004, 17(3): 236-238 |
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| 作者姓名： | 刘富东 储照虎 吴家幂 张新路 |
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| 作者单位： | 皖南医学院附属弋矶山医院,神经内科,241001;皖南医学院附属弋矶山医院,核医学科 |
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| 摘 要： | 目的 :测定急性脑血栓形成患者血清白细胞介素 - 10 (IL - 10 )的水平 ,探讨其临床意义。方法 :采用ELISA检测 5 0例病情不同程度脑血栓形成患者血清IL - 10的水平及变化 ,以 30例正常人 (对照组 )作比较。结果 :发病初期脑血栓组血清IL - 10水平显著低于对照组 (P <0 0 1) ,且随脑梗死程度加重而加重 (P <0 0 1) ,(7～ 10 )天后IL - 10水平上升。结论 :脑血栓形成可能与患者血清IL - 10水平低有关。
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| 关 键 词： | 脑血栓形成 IL-10 |
| 修稿时间： | 2004-05-14 |
Clinical Significance of Detection of Serum Levels of Interlukin 10 in Patients with Cerebral Thrombosis |
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| Liu Fudong,Zhang Xinlu,Chu Zhaohu,Wu Jiami. Clinical Significance of Detection of Serum Levels of Interlukin 10 in Patients with Cerebral Thrombosis[J]. Journal of Radioimmanology, 2004, 17(3): 236-238 |
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| Authors: | Liu Fudong Zhang Xinlu Chu Zhaohu Wu Jiami |
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| Abstract: | Objective To study the clinical significance of changes of serum levels of IL-10 in patients with cerebral thrombosis. Methods Serum levels of IL-10 in 50 patients with cerebral thrombosis and 30 controls were measured with ELISA. The IL-10 levels were again determied in randomly selected 30 of the 50 patients on d7-10. Results The serum levels of IL-10 in patients with cerebral thrombosis within 48 hours of the onset of disease were significantly higher than those in controls (P<0.01), and the larger the size of cerebral infarction, the lower the levels of IL-10. However, the levels of IL-10 measured on d7-10 were not much different from those in controls (P>0.05). Conclusion Low levels of IL-10 may play an important role in the initiation of cerebral thrombosis. |
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| Keywords: | Cerebral thrombosis interlukin-10 |
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