| 二甲双胍对高胰岛素血症儿童假性黑棘皮病的疗效观察 |
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| 引用本文： | 姜丽红,刘戈力,杨菁岩,马咸成.二甲双胍对高胰岛素血症儿童假性黑棘皮病的疗效观察[J].中华内分泌代谢杂志,2009,25(6). |
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| 作者姓名： | 姜丽红 刘戈力 杨菁岩 马咸成 |
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| 作者单位： | 天津医科大学总医院儿科,300052 |
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| 摘 要： | 对88例高胰岛素血症假性黑棘皮病(AN)肥胖儿童给予二甲双胍治疗3个月和6个月后,对空腹胰岛素、葡萄糖耐量试验2 h胰岛素和AN评分等进行评价,结果表明二甲双胍可改善假性AN肥胖患儿高胰岛素血症状态,AN分级方法可作为病情变化的无创监测手段.
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| 关 键 词： | 二甲双胍 假性黑棘皮病 高胰岛素血症 肥胖症 儿童 |
Effect of metformin on children with hyperinsulinemia and acanthosis nigricans |
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| Abstract: | Tatal 88 obese children with hyperinsulinemia and acanthosis nigricans (AN)were given metformin for 3 and 6 months.The levels of fast insulin,2 h postprandial insulin.and AN score were lower after treatment.Metformin therapy on obese children with hyperinsulinemia and AN was safe.AN score may be an appropriate non-invasive index monitoring disease prognosis. |
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| Keywords: | Metformin Aeanthosis nigricans Hyperinsulinemia Obesity:Children |
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