密蒙花黄酮类化合物的分离和鉴定

从密蒙花(Buddleia officinalis Maxim)的花蕾中分离得到8个黄酮类化合物,其小3个甙元:刺槐素(acacetin,1),芹菜素(apigenin,2),木犀草素(luteolin,3);5个甙:密蒙花新甙(neobudofficide,4),蒙花甙(linarin=acaciin,5),木犀草素7-O-芸香糖甙(6),木犀草素-7-O-葡萄糖甙(7),秋英甙(cosmosiin,8)。化合物4为新化合物,用化学和波谱法确定其结构为5.7-二羟基-4'-甲氧基黄酮-7-O-α-L-吡喃鼠李糖基-(1→2)-α-L-吡喃鼠李糖基-(1→6)]-β-D-吡喃葡萄糖甙,除化合物1和5以外,其它化合物均为首次从密蒙花中得到。

SEPARATION AND IDENTIFICATION OF THE FLAVONOIDS FROM BUDDLEIA OFFICINALIS MAXIM

The flowers of Buddleia officinalis Maxim have been used to cure eyeinflammation in China.Eight flavonoid compounds were isolated from them.Their structures werecharacterized as acacetin(1),apigenin(2),luteolin(3),neobudofficide(4),linarin(5,acaciin),luteolin-7-O-rutinoside(6),luteolin-7-O-glucoside(7)and cosmosiin(8),on the basis of chemicaland spectral evidences.The new compound 4 was identified as 5,7-dihydroxy-4'-O-methoxyflavone-7-O-α-L-rhamnopyransoyl(1→2)-α-L-rhamnopyranosyl(1→6)]-β-D-glucopyranoside and namedneobudofficide.All the compounds were isolated from B.officinalis for the first time,except linarinand acacetin.