| 1-(2,6-二甲基苯氧基)-2-(3,4-二甲氧基苯乙氨基)丙烷盐酸盐对兔血小板胞浆游离钙浓度的影响 |
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| 引用本文： | 夏敬生,罗湘,曾繁典. 1-(2,6-二甲基苯氧基)-2-(3,4-二甲氧基苯乙氨基)丙烷盐酸盐对兔血小板胞浆游离钙浓度的影响[J]. 药学学报, 1996, 31(11): 872-874 |
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| 作者姓名： | 夏敬生 罗湘 曾繁典 |
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| 作者单位： | 同济医科大学临床药理研究所 |
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| 摘 要： |
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| 关 键 词： | 1-(2 6-二甲基苯氧基)-2-(3 4-二甲氧基笨乙氨基)丙烷盐酸盐 血小板 钙离子 钙离子荧光指示剂(Fura-2) |
| 收稿时间： | 1995-09-26 |
EFFECTS OF 1-(2,6-DIMETHYLPHENOXY)-2-(3,4-DIMETHOXY PHENYLETHYLAMINO)PROPANE HYDROCHLORIDE ON CYTOSOLIC FREE CALCIUM CONCENTRATION OF RABBIT PLATELETS |
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| JS Xia,X Luo and FD Zeng. EFFECTS OF 1-(2,6-DIMETHYLPHENOXY)-2-(3,4-DIMETHOXY PHENYLETHYLAMINO)PROPANE HYDROCHLORIDE ON CYTOSOLIC FREE CALCIUM CONCENTRATION OF RABBIT PLATELETS[J]. Acta pharmaceutica Sinica, 1996, 31(11): 872-874 |
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| Authors: | JS Xia X Luo FD Zeng |
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| Abstract: | The effects of 1-(2,6-dimethylphenoxy)-2-(3,4-dimethoxyphenylethylamino)propane hydrochloride(DDPH)and verapamil on cytosolic free calcium concentratiOn of rabbitplatelets were investigated.The results showed that the elevation of cytosolic free calciumconcentration([Ca2+]i)of rabbit platelets following ionophore A23187 was significantly inhibited byDDPH and verapamil.The rates of inhibition with DDPH and verapamil were 58 % and 78 %,respectively,with no significant difference between the two groups(P>0.05). |
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| Keywords: | Platelet Ca2+ Fura-2 1-(2,6-Dimethylphenoxy)-2-(3,4-dimethoxy phenylethylamino)propanehydrochloride |
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