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胃癌CD44V6的表达与浸润转移的关系
引用本文:孙丽萍 曹敏. 胃癌CD44V6的表达与浸润转移的关系[J]. 齐齐哈尔医学院学报, 1999, 20(2): 98-100
作者姓名:孙丽萍 曹敏
作者单位:浙江医科大学附属第二医院!310009
摘    要:目的:研究胃癌CD44V6的表达与肿瘤浸润、淋巴结转移的关系。方法:应用CD44V6单克隆抗体,用S-P法免疫组织化学技术进行观察。结果:70例胃癌中24例(34.3%)CD44V6阳性。淋巴结转移组CD44V6阳性率45.7%明显高于无转移组的12.5%(X^2=11.24,P〈0.01);结论:提示CD44V6的表达可作为预测胃癌转移的较好指标。

关 键 词:CD44V6 胃癌 免疫组化 肿瘤浸润

Correlation of Expressions of CD_(44V6)with Infiltration and Metastasis of Gastric Carcinoma
Sun Liping et al. Correlation of Expressions of CD_(44V6)with Infiltration and Metastasis of Gastric Carcinoma[J]. Journal of Qiqihar Medical College, 1999, 20(2): 98-100
Authors:Sun Liping et al
Affiliation:The Second affiliated Hospital of Zhejiang Medical University
Abstract:To study correlation of expressions of CD_(44V6) in gastic Carcinoma with infiltration of the tumor and Lymphatic metastasis .Methoes : The tumors were investigated by S - P immunohistochemical techique using mono clonal antibody for CD_(44V6). Results :Out of 70 cases with the tumor , 24 cases (34.3% )were positive for CD_(44V6), The posi -tive rate of CD_(44V6)(45. 7% )in the ase with the metastasis was significantly higher thand that (12. 5% )in the cases without the metastasis (X~2 = 11 .24, P <0. 01) . Conclusions :It suggested that CD_(44V6) may be an useful criteria for evaluation ofmetastasis in the tumor .
Keywords:CD_(44V6) Gastric carcinoma Immunohistochenmistry
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