黛力新辅助雌激素替代疗法治疗更年期心理精神障碍

目的:探讨氟哌噻吨辅助雌激素替代疗法治疗更年期精神障碍的效果。方法:对80例更年期精神障碍患者分别给予黛力新+雌激素替代疗法或单纯雌激素替代治疗,在治疗前后应用症状自评量表(SCL-90)进行评分比较。结果:两组治疗前的评分比较无差异(P>0.05);治疗前后相比均有差异(P<0.01);治疗6个月后除强迫一项外,其他项目均有差异(P<0.05或P<0.01)。结论:氟哌噻吨联合雌激素治疗更年期精神障碍是有效的,且较单纯雌激素替代疗法好。

Flupenthixol/melitracen assistant estrogen replacement therapy in treatment for climacteric mental disorders

Objective:To investigate the psychological disorder among the patients of climacteric syndrome and explore the therapeutic effect of flupenthixol/melitracen assistant estrogen replacement therapy.Methods:80 patients were assigned randomly into test group (treated with flupenthixol/melitracen assistant estrogen replacement therapy) and control group, each of which were marked by symptom checklist90 (SCL-90) before and after the treatment, respectively.Results:The scores between the two groups were similar (P>0.05) before treatment. In test group, the scores decreased significantly after treated for 6 months (P<0.01).Compared with those before therapy, while control group had little change. The scores but one aspect between the two groups were different after treated for 6 months (P<0.05 or P<0.01).Conclusion:The climacteric patients with psychological disorder could be treated effectively by flupenthixol/melitracen assistant estrogen replacement therapy, the effect of which is better than that of estrogen replacement therapy alone.