| 剥夺睡眠对人体免疫功能的影响 |
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| 引用本文： | 裘宇容,洪军,杨春莉.剥夺睡眠对人体免疫功能的影响[J].南方医科大学学报,1999,19(4):337-338. |
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| 作者姓名： | 裘宇容 洪军 杨春莉 |
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| 作者单位： | 1. 第一军医大学南方医院检验科,广州,510515
2. 第一军医大学南方医院康复科,广州,510515 |
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| 摘 要： | 目的探讨睡眠与免疫功能的关系。方法采用流式细胞仪和单向琼脂扩散法对20例军校学员进行了剥夺睡眠48h后细胞免疫和体液免疫功能的测定。结果剥夺睡眠48h后，T细胞亚群CD4、CD8以及免疫球蛋白lgG、IgA、IgM和补体C3、C4的含量与剥夺睡眠前相比无显著性差异（P>0.05），NK细胞值则显著降低（P＜0．01）。结论剥夺睡眠48h对人体免疫功能有影响，睡眠与免疫功能有关。
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| 关 键 词： | 剥夺睡眠 免疫功能 |
| 修稿时间： | 1999-03-28) |
Effects of sleep deprivation on human immune function |
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| Qiu Yurong,Yang Chunli,Hong Jun.Effects of sleep deprivation on human immune function[J].Journal of Southern Medical University,1999,19(4):337-338. |
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| Authors: | Qiu Yurong Yang Chunli Hong Jun |
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| Abstract: | objective To Study the relationship of sleep to immune functions. Method The effect of 48 h sleep deprivation on someimmune function of 20 military students was studied by flow cytometer and simple agar diffesion test. Result 48 h sleepdeprivation led to decreased the percentage of NK cells significantly, but the percentapes of CD3. CD4. CD8 and contents ofimmunoglobulin IgG. IgA. IgM and complements C3. C4 was unaffected. Conclusion Sleep deprivation can affect on humanimmune,function and sleep is associated with immune function. |
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| Keywords: | sleep deprivation immune function |
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