| 高浓度尼莫地平注射液的研制 |
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| 引用本文： | 陈桂兰,王巧.高浓度尼莫地平注射液的研制[J].中国医药工业杂志,1997,28(6):254-256. |
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| 作者姓名： | 陈桂兰 王巧 |
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| 作者单位： | 河北医科大学药学系药剂学教研组，河北医科大学药学系 |
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| 摘 要： | 采用正交设计实验法，优选出较高浓度的尼莫地平注射液处方，它由药物、乙醇、ＰＥＧ４００和水组成。并对其可稀释性、热稳定性和光稳定性等进行了初步考查。
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| 关 键 词： | 尼莫地平 注射剂 制备 正交设计法 稳定性 |
PREPARATION OF NIMODIPINE INJECTION OF HIGHER CONCENTRATION |
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| Authors: | CHEN Gui Lan WANG Qiao ZHANG Jian Feng LIU Wei Na ZHANG Xiu Ying |
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| Institution: | CHEN Gui Lan *,WANG Qiao,ZHANG Jian Feng,LIU Wei Na,ZHANG Xiu Ying |
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| Abstract: | The optimal formulation of nimodipine injection of higher concentration was found by orthogonal design method.It consists of this drug,ethanol,PEG 400 and water.Its compatibility with aqueous infusions and the stability of drug against light and heat were studied preliminarily. |
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| Keywords: | nimodipine injection orthogonal design preparation stability |
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