| 缓释制剂体外溶出考察方法的探讨 |
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| 引用本文： | 陈镇生. 缓释制剂体外溶出考察方法的探讨[J]. 中国医药工业杂志, 1997, 28(1): 43-47 |
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| 作者姓名： | 陈镇生 |
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| 作者单位： | 浙江省药品检验所 |
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| 摘 要： | 建立体外溶出度检查方法，使之能控制控释或缓释制剂的质量并能检出批间是否生物等效，最好是在体内释放曲线的基础上寻找具有与其相关性最好的体外溶出曲线的检查方法。
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| 关 键 词： | 体外溶出曲线 体内释放曲线 溶出度 缓释制剂 |
ESTABLISHMENT OF A SUITABLE DISSOLUTION METHOD FOR CONTROLLED/SUSTAINED RELEASE DOSAGE FORMS |
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| ). ESTABLISHMENT OF A SUITABLE DISSOLUTION METHOD FOR CONTROLLED/SUSTAINED RELEASE DOSAGE FORMS[J]. , 1997, 28(1): 43-47 |
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| Authors: | ) |
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| Abstract: | To establish a good dissolution in vitro that can effectively control the quality of controlled/sustained release dosage forms and show if they are bioequivalent betwean batches ,the best method is to find out the dissolution curve which is significant correlation with the release curve on the basis of the in vivo release kinetics . |
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| Keywords: | dissolution in vivo release kinetics controlled/modified release dosage forms |
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