48例视网膜血管瘤的临床特征

目的了解视网膜血管瘤的临床特征.方法对48例视网膜血管瘤的临床资料进行回顾性分析.结果 48例患者中,男女比例相同,青壮年患病较多.其中双眼患病13例(27%),多发性血管瘤22只眼(36%),von Hippel Lindou(VHL)病患者17例(35%),单发性视网膜血管瘤均位于视网膜颞侧.有症状的血管瘤直径均≥1个视盘直径.患者就诊原因依次为视力下降41只眼(77%),眼前黑影飘动8只眼(15%),视物变形4只眼(8%).患病≤1个月就诊者,平均视力为0.5;≥6个月就诊者,>90%的患者视力≤0.05.结论视网膜血管瘤是一种易累及双眼并主要危害青壮年视力的少见眼底病.

Clinical features of 48 cases with retinal angioma

Objective To summarize the clinical features of 48 cases with retinal angioma. Methods The 48 cases were retrospectively summarized. The clinical features included sex distribution, age at first visit, chief complains, visual acuity, and the size, number and site of retinal angioma identified by fundus fluorescein angiography (FFA) and fundus examination. Results There were 24 males and 24 females. The mean age at onset was 27 years. Thirteen cases (27%) had bilateral retinal angiomas. Multiple angiomas were found in 22 eyes (36%). Seventeen cases (35%) were identified as von Hippel Lindau (VHL) disease. The location of angioma was in the temporal retina in all the cases with only one angioma. All the symptomatic tumors were larger than 1 disc diameter (DD). The common symptoms of patients with retinal angioma were visual loss in 77% cases, floaters in 15% cases and distortion in 8% cases. Conclusion Retinal angioma is an uncommon disease prone to be involved in both eyes and to primarily damage the vision of young and middle aged adults.