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膜引导组织再生作用的实验研究(二)胶原膜结合羟基磷灰石在骨缺损修复中的应用
引用本文:陈江,吴东,林珊,黄文秀,姚丽艳. 膜引导组织再生作用的实验研究(二)胶原膜结合羟基磷灰石在骨缺损修复中的应用[J]. 中国口腔种植学杂志, 1999, 0(2)
作者姓名:陈江  吴东  林珊  黄文秀  姚丽艳
作者单位:福建医科大学口腔系,福州市铁路中心医院,福建医科大学附一院
摘    要:为了了解羟基磷灰石(HA)对膜引导骨再生作用的影响,将20只日本纯种大耳兔分为两组,一组在股骨中植入胶原膜和HA颗粒,另一组植入胶原膜,分别在于术后2,3,4,6,8周处死动物,标本进行大体观察,X线透视,光镜组织学检查。结果表明,膜结合HA组的新骨生长速度和成骨质量均较单纯膜组好。提示胶原膜结合HA颗粒在引导骨组织再生方面具有协同作用。

关 键 词:胶原膜  羟基磷灰石  骨再生作用

The Experimental Study of Guided Tissue Regenerationby Collagen Membrane Combined with Hydroxyapatite
Chan Jiang,Wu Dong,Lin Shang,et al. The Experimental Study of Guided Tissue Regenerationby Collagen Membrane Combined with Hydroxyapatite[J]. Chinese Journal of Oral Implantology, 1999, 0(2)
Authors:Chan Jiang  Wu Dong  Lin Shang  et al
Affiliation:Chan Jiang,Wu Dong,Lin Shang,et al Department of Stomatology.Fujian Medical University
Abstract:The Purpose of the present study was to determine whether the use of hydroxypapatite in conjunction with collagen membrane influenced the new bone regeneration. 4 mm diameter bone defect was created in twenty adult Japan white rabbits femur.The defets of 10 rabbits were covered by collagen membranes,the others were filled with hydroxyapatite and then covered by collagen membranes.All animals were killed at 2nd,3rd,4th,6th,8th weeks after operation respectively.The samples were observed for radiology and histology.The result showed that collagen membranc combined with HA could improve new bone regeneration.
Keywords:collagen membrane hydroxyapatite bone regeneration
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