Magnetic resonance imaging determination of gliomatosis cerebri |
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Authors: | M V Spagnoli R I Grossman R J Packer D B Hackney H I Goldberg R A Zimmerman L T Bilaniuk |
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Institution: | (1) Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA;(2) Division of Neurology and Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA;(3) Department of Neurology and Pediatrics, University of Pennsylvania, Philadelphia, Pennsylvania, USA |
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Abstract: | Summary Gliomatosis cerebri is a rare condition characterized by diffuse overgrowth of large portions of the brain and spinal cord by glial cells in varying stages of differentiation. The tumor process is primarily an infiltrative, rather than a destructive one. Hence, pre-operative diagnosis by traditional imaging studies, including computed tomography (CT), has been difficult. Magnetic resonance imaging (MRI), with its unique sensitivity for cerebral pathology, is an ideal modality for demonstrating this lesion. We present three cases of gliomatosis cerebri in which high-field MRI clearly delineates the extent of the pathologic process. |
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Keywords: | Gliomatosis cerebri MRI |
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