| 中性粒细胞弹性蛋白酶在寻常型银屑病患者血清中的表达及意义 |
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| 引用本文： | 耿庆娜.中性粒细胞弹性蛋白酶在寻常型银屑病患者血清中的表达及意义[J].岭南皮肤性病科杂志,2012(5):276-278. |
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| 作者姓名： | 耿庆娜 |
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| 作者单位： | 开封市第二人民医院皮肤科,河南开封475000 |
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| 摘 要： | 目的：探讨中性粒细胞弹性蛋白酶（neutrophi lelastase，NE）在寻常型银屑病发病中的作用和意义。方法：实验组寻常型银屑病患者40例，对照组40例，采用酶联免疫吸附法检测两组人群血清中NE的表达。结果：寻常型银屑病患者血清中NE的表达水平明显高于对照组（t=9．07，P〈0．01），表达水平与病情严重程度相关（r=O．828，P〈0．01）。结论：NE在寻常型银屑病患者血清中高表达，且与疾病严重程度呈正相关。
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| 关 键 词： | 银屑病 寻常型 中性粒细胞弹性蛋白酶 |
Expression and Implication of Neutrophil Elastase in Serum of Patients with Psoriasis Vul garis |
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| GENG Qing-na.Expression and Implication of Neutrophil Elastase in Serum of Patients with Psoriasis Vul garis[J].Southern China Journal of Dermato-Venereology,2012(5):276-278. |
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| Authors: | GENG Qing-na |
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| Institution: | GENG Qing-na (Department of Dermatology, The Second People＇s Hospital of Kaifeng , Kaifeng 475000, China) |
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| Abstract: | Objective： To explore the role of NE in the pathogenesis of psoriasis vulgaris. Methods： Venous blood was collected from 40 individuals with psoriasis vulgaris and 40 control in- dividuals without psoriasis. NE was detected by enzyme-linked immunosorbent assay. Results：Ex pression level of NE in serum of patients with psoriasis vulgaris was significantly higher than that of normal controls （ t=9. 07 ,P 〈0. 01 ）, and expression level of NE was positively related to severity of illness （ r = 0. 828, P 〈 0. 01 ）. Conclusion： Expression level of NE is high in patients with pso riasis vulgaris and it may indicate severity of illness. |
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| Keywords: | Psoriasis Vulgaris NE |
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