血尿酸水平与冠心病患者的临床特征及冠脉造影结果的关系

目的 探讨血尿酸水平与冠心病患者的临床特征及冠脉造影结果的关系.方法 将207例行冠状动脉造影(CAG)的患者分为对照组和冠心病组,然后对两组患者的临床资料和CAG结果进行统计学分析.结果 血尿酸水平在冠心病组明显高于对照组(P＜0.05),血尿酸水平与冠脉病变的支数和ACC/AHA评分有关(P＜0.05).按临床分型后急性冠脉综合征(ACS)组血尿酸水平显著高于稳定型心绞痛(SAP)组(P＜0.05).按冠脉病变的支数分组后,多支病变组血尿酸水平明显高于对照组(P＜0.05).结论 高尿酸血症是冠心病的一个危险因素,与冠状动脉狭窄程度相关,对预测急性冠脉事件的发生和发展有一定的价值.

The Relationship between Serum Uric Acid and Clinic Characteristics and Reset of Coronary Artery Angiography of Patients with Coronary Heart Disease

Objective To investigate the relationship between serum uric acid(SUA)and clinic characteristics and result of coronary artery angiography of patients with coronary heart disease(CHD).Methods Two hundreds and seven patients for coronary artery angiography were divided into CHD group and control group.Their clinical data and results of coronary artery angiography were analyzed through statistics.Results SUA levels of CHD patients were significantly higher than the control subjects SUA(P <0.05).The levels of SUA related with the numbers of stenosed branch and the ACC/AHA scores(P<0.05).The concentration of SUA in patients with ACS was obviously higher than that in patients with SAP(P<0.05).Compared with that in the control group,the level of SUA in triple-vessel group was higher(P<0.05).Conclusions Hyperuricemia is one of risk factors for patients with CHD and closely related with the severity of coronary artery lesion.The levels of SUA may predict occurrence and development of acute coronary heart disease events.