| 神经营养因子与糖尿病性勃起功能障碍 |
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| 引用本文： | 陈赟,戴玉田,孙则禹. 神经营养因子与糖尿病性勃起功能障碍[J]. 中华男科学杂志, 2006, 12(3): 263-266 |
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| 作者姓名： | 陈赟 戴玉田 孙则禹 |
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| 作者单位： | 南京大学医学院附属鼓楼医院泌尿外科,江苏,南京,210008 |
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| 基金项目： | 江苏省卫生厅"135工程"医学重点人才基金;江苏省社会发展基金 |
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| 摘 要： | 目前研究表明,神经营养因子在各类神经的发育、分化和再生过程中发挥了重要作用。局部神经营养因子的异常变化是糖尿病性周围神经病变的发病机制之一。糖尿病性勃起功能障碍发病原因众多,而其中重要的一点就是勃起神经的损伤。神经营养因子对于勃起神经损伤导致的勃起功能障碍有明确的治疗作用,最近发现其对糖尿病性勃起功能障碍实验动物也有类似效果。神经营养因子对治疗糖尿病性勃起功能障碍开辟了一条新的思路。
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| 关 键 词： | 神经营养因子 糖尿病 勃起功能障碍 |
| 文章编号： | 1009-3591（2006）03-0263-04 |
| 收稿时间： | 2005-09-27 |
| 修稿时间： | 2005-12-20 |
Neurotrophin and Erectile Dysfunction in Diabetes |
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| CHEN Yun,DAI Yu-tian,SUN Ze-yu. Neurotrophin and Erectile Dysfunction in Diabetes[J]. National journal of andrology, 2006, 12(3): 263-266 |
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| Authors: | CHEN Yun DAI Yu-tian SUN Ze-yu |
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| Affiliation: | Department of Urology, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing , Jiangsu 210008, China |
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| Abstract: | Neurotrophins play significant roles in the development, differentiation and regeneration of many neurons. The abnormal changes of neurotrophins are one of the nosogenesis of diabetic peripheral neuropathy. Erectile dysfunction (ED) in diabetes is multifactorial and one of the most important causes is the injury of pelvic splanchnic nerves. Neurotrophins therapy shows exact effects on ED with pelvic splanchnic nerves injured. Recent researches indicates that the same treatment has the similar therapeutic effects on the ED animals with diabetes. Neurotrophins therapy develops a new way for us to cure the ED with diabetes. |
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| Keywords: | neurotrophin diabetes mellitus erectile dysfunction |
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